MSH White Solubility and Mixing with Existing Cream/Toner

Asked by: rungmoney2561 On: December 26, 2022 Product Type: Cosmetics

Question

I have questions about dissolving MSH White™ in alcohol and mixing it into existing cream or toner bases:

  1. If MSH White™ is dissolved in alcohol and then mixed into a pre-made cream base, will it precipitate back into solid form like before dissolving?
  2. If MSH White™ is dissolved in alcohol and then mixed into a water-based product like a toner, will it return to its powder form like before dissolving?
  3. What is the required ratio of alcohol to MSH White™ for dissolution?
  4. Does dissolving MSH White™ in alcohol require heat?

My objective is to mix MSH White™ with existing cream or toner, not to formulate the cream base myself. Thank you.

Answer

MSH White™ Solubility and Usage

Based on the product information for MSH White™ (Undecylenoyl phenylalanine), here are the answers to your questions regarding dissolving it in alcohol and mixing with existing cream or toner:

  1. Precipitation in cream: MSH White™ is soluble in oil or the oil phase of a formula (with heat at 80°C) and also in alcohol (at least 60°C). If you dissolve it in alcohol and add it to a pre-made cream base, it might precipitate depending on the composition of the cream base. The product information primarily recommends dissolving it in the oil phase. Adding an alcohol solution to a finished cream could potentially disrupt the emulsion or exceed the solubility limit in the final mixture, leading to precipitation.

  2. Precipitation in water/toner: MSH White™ is not water-soluble. If you dissolve it in alcohol and add it to a water-based product like a toner, it is highly likely to precipitate and return to its powder form.

  3. Alcohol ratio for dissolution: The product information states that MSH White™ can be dissolved in alcohol at a temperature of at least 60°C, but it does not specify the exact ratio of alcohol required to dissolve a certain amount of MSH White™.

  4. Heat for dissolution in alcohol: Yes, according to the product information, dissolving MSH White™ in alcohol requires heat, specifically a temperature of at least 60°C.

Given that you intend to mix with existing cream or toner and not create a formulation from scratch, dissolving in alcohol with heat (>= 60°C) is a possible method, but be aware of the high risk of precipitation, especially in water-based toners. For creams, the outcome depends heavily on the cream's specific composition.

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