pH Compatibility of Ingredients in Serum Formulation

Asked by: nu_nu_beer On: December 08, 2015 Product Type: Cosmetics

Question

Could you please advise on the pH compatibility of the following ingredients in a serum formulation?

  • TreMoisture™ (Trehalose)
  • Pep®-Coll (Syn-Coll)
  • Argireline®
  • Vitamin E
  • MSH White Absorb™
  • Geranium Oil

Specifically:

  1. Are these ingredients stable and effective at a pH of 5-5.5?
  2. Is it generally true that oil-based ingredients (like Vitamin E, MSH White Absorb™, Geranium Oil) are less sensitive to pH variations compared to water-soluble ingredients?

Answer

Based on the staff's response:

  • Ingredients without a specified optimal pH are generally stable in a neutral to slightly acidic range (pH 4.5-7.0).
  • All the ingredients you listed (TreMoisture™ (Trehalose), Pep®-Coll (Syn-Coll), Argireline®, Vitamin E, MSH White Absorb™, Geranium Oil) are compatible with a product pH of 5-5.5.
  • Your understanding is correct: oil-based ingredients (Vitamin E, MSH White Absorb™, Geranium Oil) are less sensitive to pH variations and can typically be added to products with a wider pH range.

Related Products Mentioned

Acetyl Hexapeptide-8 (eq Argireline)
Pep®-Coll (Palmitoyl tripeptide-5)
Vitamin E (dl-alpha tocopherol)
TreMoisture™ (Trehalose)
MSH White Absorb™

Tags

Ingredient Suitability Oil Compatibility Serum Stability pH Compatibility