Precipitate in LHA Serum Formula due to Refrigeration

Asked by: fah_3058 On: September 25, 2014 Product Type: Cosmetics

Question

I have a serum formula containing LHA, B5, B3, AHA, and water. A white precipitate formed after storing it in the refrigerator. I plan to use heat to dissolve the precipitate. Will using heat damage the efficacy of the other ingredients in the formula?

Answer

Subject: Precipitate in LHA Serum Formula

Hello,

Regarding the white precipitate in your serum formula containing LHA, B5, B3, AHA, and water, it is highly likely that the precipitate formed due to storing the product in the refrigerator, especially if it was too cold. LHA (and BHA) ingredients are known to precipitate at low temperatures. Formulas containing these ingredients should generally not be refrigerated.

To fix the current batch:

  • Allow the product to return to room temperature.
  • If the precipitate remains, gently warm the product (e.g., to 40-50°C) and stir or shake until the precipitate dissolves. Avoid using excessive heat.

For future batches and long-term stability:

  • Avoid storing the product in the refrigerator.
  • Consider adding a small amount of a gel maker, such as Pro Polymer (e.g., 0.2%), to the formula. This helps stabilize the ingredients and prevents precipitation while keeping the texture liquid like a toner.

Regarding the concern about heat degrading ingredients: While high heat can degrade some ingredients, the moderate heat used to redissolve the precipitate in this case is a common practice in cosmetic formulation and should not significantly impact the efficacy of your ingredients. Use just enough heat to dissolve the precipitate.

Hope this helps!