Pterostilbene Effectiveness in Serum without Ethanol or Propylene Glycol

Based on the product information found, the effectiveness of Pterostilbene in a serum without ethanol or Propylene Glycol depends on the specific type of Pterostilbene used.

Here's a breakdown:

• Pure-Pterostilbene™ (98%): This form of Pterostilbene is described as soluble in ethanol and Propylene Glycol. The product description explicitly states that the formula must include ethanol or Propylene Glycol to help dissolve it. Simply dispersing this type in a serum without these solvents means it is unlikely to dissolve properly. If it remains in solid or crystalline form, it cannot effectively penetrate the skin or exert its intended effects. Therefore, for this type, the absence of ethanol or Propylene Glycol would likely render it ineffective.

• ActiveRelease™ Pterostilbene (Encapsulation): This is an encapsulated form of Pterostilbene designed to dissolve directly in water and permeate the skin. Its solubility is listed as "Can be dissolved in water." This encapsulated version does not require ethanol or Propylene Glycol for dissolution and can be mixed into the water phase of a formulation. If you are using this specific encapsulated form, it can be effective in a serum without ethanol or Propylene Glycol because it is designed for water-based systems.

In summary, if you are using the standard Pure-Pterostilbene™ (98%), it is unlikely to be effective without ethanol or Propylene Glycol to dissolve it, even if dispersed. However, if you are using the ActiveRelease™ encapsulated version, it is water-soluble and can be effective in a serum without these solvents.