Recommended Concentration for Myristyl Nicotinate Around the Eyes

Based on your goal to use an ingredient with minimal irritation for the sensitive eye area, and considering the properties of Myristyl Nicotinate (Pro-Niacin™ / Max-B3™) compared to Niacinamide (Vitamin B3, Safe-B3™), a suitable concentration for Myristyl Nicotinate around the eyes is 3%.

Here's why:

• Myristyl Nicotinate vs. Niacinamide: While both are related to Vitamin B3, Myristyl Nicotinate has a different structure that allows for better skin absorption and, importantly, does not cause the flushing (redness) side effect associated with free niacin found in some Niacinamide products. High-purity Niacinamide like Safe-B3™ or Extreme-B3™ significantly reduces this free niacin, making them less likely to cause flushing than standard Niacinamide, but Myristyl Nicotinate avoids this issue altogether.
• Irritation Potential: Although Myristyl Nicotinate doesn't cause flushing, any active ingredient can potentially cause irritation, especially on sensitive skin areas like around the eyes. The manufacturer's recommended usage rate for Myristyl Nicotinate on the face is typically 3-10% (with 5-6% recommended). Products on the market use it up to around 5% for facial application, which often includes the eye area.
• Recommendation for Eye Area: Given the sensitivity of the skin around the eyes, using a lower concentration than the maximum recommended for the face is a good practice. A 3% concentration of Myristyl Nicotinate is considered sufficient to provide benefits for the eye area while minimizing the risk of irritation, offering a balance between efficacy and gentleness.

In summary, while Safe-B3™ Niacinamide might be recommended at a lower percentage (e.g., up to 2%) for the eye area due to potential residual niacin sensitivity, Myristyl Nicotinate (Max-B3™) at 3% is a recommended starting point for this delicate area, offering effective benefits without the flushing side effect.