Recommended Low-Odor Volatile Silicone Replacements for Serum (LipidSoft D5 Substitute)

Asked by: supats.panisaoil On: October 29, 2025 Product Type: Cosmetics

Question

I am looking for a suitable substitute for LipidSoft™ D5 (Cyclomethicone Replacer) to use in a clear facial serum formulation at a concentration of 34%. The current ingredient has a strong chemical odor, which I need to eliminate. The replacement must meet the following criteria:

  • Be approved by the Thai FDA (not prohibited).
  • Function as a volatile silicone alternative.
  • Provide excellent volatility, slip, cushion, and overall aesthetics.
  • Have a very low or non-chemical odor.

Answer

Recommended Volatile Silicone Replacements

Based on your requirement for a volatile silicone alternative that provides excellent volatility, slip, cushion, and aesthetics, can be used at 34% concentration, and is Thai FDA-approved (non-prohibited), we highly recommend Dodecane (Natural Cyclopentasiloxane Replacement), as suggested by the administrator.

Primary Recommendation: Dodecane (Natural Cyclopentasiloxane Replacement)

Dodecane (ID: 35516) is an excellent, natural-origin substitute for Cyclopentasiloxane (D5) and is fully compliant with Thai FDA regulations. It is a highly effective replacement for LipidSoft™ D5.

  • Volatility & Aesthetics: It offers a very high volatility profile, similar to D5, ensuring a dry, non-greasy finish. It provides superb slip and cushion, making it ideal for serums and clear emulsions.
  • Usage Rate: It can be used safely at high concentrations, including your target of 34%, as it is a light, volatile emollient.
  • Odor: It has a very low, almost undetectable odor, meeting your requirement for a non-chemical smell.

Alternative Option: LipidSoft™ Cyclo

For another high-performance, natural-based option that meets all criteria, consider LipidSoft™ Cyclo (e.q. Cetiol Ultimate) (ID: 7969).

  • Performance: This ingredient is known for its extremely high volatility and light, dry feel, often surpassing D5 in terms of quick absorption and non-tacky finish.
  • Application: It is perfect for replacing volatile silicones in clear serums, sprays, and light emulsions, offering excellent spreadability and a silky touch.
  • Usage Rate: Like Dodecane, it is suitable for high usage rates, easily accommodating 34% in your formula.

Both Dodecane and LipidSoft™ Cyclo are excellent, FDA-approved choices that meet all your criteria for replacing LipidSoft™ D5 while maintaining superior sensory properties.