Refrigeration for Peptide Gel Stability

Asked by: air_write On: March 28, 2013 Product Type: Cosmetics

Question

Should a finished gel formulation containing sensitive peptides such as Syn®-Coll (Palmitoyl tripeptide-5) and Matrixyl™ 3000 (Pal-GHK, Pal-GQPR) be stored in the refrigerator? What are the reasons for this storage recommendation?

Answer

Refrigeration of Peptide Gels

Yes, it is generally recommended to store finished gel formulations containing sensitive peptides like Syn®-Coll (Palmitoyl tripeptide-5) and Matrixyl™ 3000 (Pal-GHK, Pal-GQPR) in the refrigerator.

Storing the gel in the refrigerator helps to:

  • Protect from light and heat: Peptides can be sensitive to degradation from light and high temperatures.
  • Slow down microbial growth: Lower temperatures inhibit the growth of bacteria and other microorganisms, which helps maintain the stability and safety of the product over time.

While the formulation includes preservatives, refrigeration provides an extra layer of protection, extending the shelf life and ensuring the efficacy of the sensitive active ingredients.

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