Review and Adjustments for Melasma, Wrinkle, and Dry Skin Formulations

Asked by: thaipppp On: June 16, 2017 Product Type: Cosmetics

Question

I have two cosmetic formulations targeting melasma, wrinkles, and dry skin. I would like advice on whether I need to adjust the pH or make any other changes to the formulas.

Formula 1: Melasma, Wrinkles, Dry Skin

  1. น้ำกลั่น ปราศจากเชื้อ
  2. Light Cream Maker™ 1%
  3. Activated Resorcinol™ 1%
  4. Safe-B3™ (Vitamin B3, Niacinamide) 5%
  5. Tranexamic Acid (Trans-White™) 3%
  6. LipidSoft™ 5%
  7. Reservoir-Tech (กักเก็บส่วนผสมใต้ผิว) 3%
  8. Bisabolol (German Chamomile Extract) 1%
  9. isopropyl myristate 4%
  10. Phenoxyethanol SA (Optiphen Plus) 1%

Formula 2: Melasma, Dark Spots, Wrinkles, Moisturizing (Dry Skin)

  1. water
  2. Galactomyces Ferment Filtrate (Pitera) 37%
  3. Rose Hip Oil (Extra Virgin Organic Fresh) 2.5%
  4. Activated Resorcinol™ .05%
  5. Bisabolol (German Chamomile Extract) .05%
  6. isopropyl myristate 1.5%
  7. Light Cream Maker™ .05%

Do I need to adjust the pH or increase/decrease anything in these formulas?

Answer

Formulation Review and Recommendations

Here is a review of your two formulas for melasma, wrinkles, and dry skin, along with recommendations for adjustments.

Formula 1: Melasma, Wrinkles, Dry Skin

This formula contains good active ingredients for targeting melasma and wrinkles, such as Activated Resorcinol, Safe-B3 (Niacinamide), and Tranexamic Acid. It also includes moisturizing and skin-conditioning ingredients like LipidSoft, Reservoir-Tech, Bisabolol, and Isopropyl Myristate, along with Light Cream Maker as an emulsifier and Phenoxyethanol SA as a preservative.

Recommendations for Formula 1:

  • pH Adjustment: The optimal pH range for Activated Resorcinol is 4.5-5.5, and Phenoxyethanol SA works best in the range of 2.0-6.0. Safe-B3 and Tranexamic Acid have broader compatible ranges (3-8). To ensure the best efficacy and stability of your active ingredients and preservative, adjust the final pH of the formula to be within the range of 4.5-5.5.
  • Stability Enhancers: Activated Resorcinol can discolor over time, and Tranexamic Acid can also experience long-term discoloration. To help prevent this, it is recommended to add 0.2% Disodium EDTA and 0.5% ActiveProtec™ OX to the formula.
  • Ingredient Percentages: The percentages used for most ingredients are within the recommended ranges. However, you mentioned "LipidSoft™" without specifying the type. Ensure the specific type of LipidSoft™ you are using is suitable for your desired texture and does not cause issues like clogging at the 5% concentration, especially for acne-prone skin (e.g., LipidSoft Palm might clog pores at higher amounts, while LipidSoft Lite is very light). The 1% concentration of Light Cream Maker is suitable for emulsifying 5% oil.

Formula 2: Melasma, Dark Spots, Wrinkles, Moisturizing (Dry Skin)

This formula utilizes Galactomyces Ferment Filtrate (Pitera) as a base, combined with Rose Hip Oil, Activated Resorcinol, Bisabolol, Isopropyl Myristate, and Light Cream Maker.

Recommendations for Formula 2:

  • pH Adjustment: Similar to Formula 1, the optimal pH range for Activated Resorcinol is 4.5-5.5. Galactomyces Ferment Filtrate has a pH range of 4-7, which is compatible. Adjust the final pH of the formula to be within the range of 4.5-5.5 for optimal Activated Resorcinol efficacy and overall stability.
  • Stability Enhancers: Add 0.2% Disodium EDTA to help prevent discoloration of Activated Resorcinol.
  • Ingredient Percentages: Several percentages are below the recommended minimum usage rates for efficacy:
    • Activated Resorcinol: Increase from 0.05% to at least 0.1%, and ideally up to 1% for better efficacy against melasma and dark spots in a leave-on product.
    • Bisabolol: Increase from 0.05% to at least 0.5%, and ideally 1%, for its anti-irritant and skin-benefiting properties.
    • Light Cream Maker™: Increase from 0.05% to at least 0.5% to function correctly as an emulsifier and thickener. To achieve a cream texture with 2.5% oil, a concentration of 1-1.5% is likely needed.
    • Water: Adjust the percentage of water downwards to accommodate the increased percentages of the other ingredients, ensuring the total formula adds up to 100%.
    • Galactomyces Ferment Filtrate: The 37% concentration is high and within the acceptable range (1-100%), but be aware that high doses might feel slightly greasy according to the product description.

By making these adjustments, you can enhance the effectiveness and stability of your formulations.