Review and Questions about Skin Whitening Cream Formulation

Asked by: wasanwsn On: August 08, 2015 Product Type: Cosmetics

Question

Please critique my skin whitening cream formulation so I can adapt it further:

  • Water (EDTA) = 84%
  • LipidSoft™ = 5%
  • N-Acetyl-D glucosamine (GlucoBright™) = 5%
  • Vitamin B3, Niacinamide (Safe-B3™) = 3%
  • Activated Resorcinol™ (4-butyl Resorcinol) = 2%
  • Light Cream Maker™ = 1%

I noticed that Activated Resorcinol™ (4-butyl Resorcinol) is recommended by the admin for use at no more than 1% in skin creams, but to prevent the degradation of the substance, I will use 2%. Will this cause any problems?

The three substances N-Acetyl-D glucosamine (GlucoBright™), Vitamin B3, Niacinamide (Safe-B3™), Activated Resorcinol™ (4-butyl Resorcinol) were recommended by the admin as working well together, so I have adapted them for use. Please provide any further suggestions.

Answer

Review of Your Skin Whitening Cream Formulation

Thank you for sharing your skin whitening cream formulation. Let's review the ingredients and your question about the Activated Resorcinol concentration.

Your formulation includes several effective ingredients for skin whitening and overall skin health:

  • Water (with EDTA): The base of the cream. EDTA helps to chelate metal ions in the water, improving the stability of the formulation.
  • LipidSoft™: This acts as an emollient, providing a soft and smooth feel to the skin without being oily.
  • GlucoBright™ (N-Acetyl-D Glucosamine): Works as a whitening agent, helps reduce dark spots, and stimulates the skin's natural production of Hyaluronic Acid for moisture.
  • Safe-B3™ (Vitamin B3, Niacinamide): A versatile ingredient that helps reduce wrinkles, redness, hyperpigmentation, improves skin barrier function, controls oiliness, and can be used for dark circles.
  • Activated Resorcinol™ (4-butyl Resorcinol): A potent whitening agent that works by reducing tyrosinase activity and preventing pigment transfer.
  • Light Cream Maker™: This is the emulsifier and thickener that helps create the cream texture.

Regarding Activated Resorcinol™ Concentration

You mentioned increasing the Activated Resorcinol™ concentration to 2% to prevent degradation, noting that the administrator recommended not exceeding 1% for skin creams.

According to the product information for Activated Resorcinol™, the recommended usage rate for leave-on products (like creams or gels) is not more than 1%. This is because Activated Resorcinol™ is highly effective, and using higher concentrations can potentially cause skin irritation.

While it is light-sensitive and should be protected from light (e.g., by using opaque packaging), increasing the concentration beyond the recommended limit is not the standard method to prevent degradation and could lead to adverse skin reactions. The inclusion of Disodium EDTA in your formula is a good step, as it is recommended to help prevent discoloration of Activated Resorcinol™.

It is best to adhere to the recommended maximum usage rate of 1% for Activated Resorcinol™ in leave-on formulations to ensure both effectiveness and skin safety.

Combination of Whitening Agents

You are correct that N-Acetyl-D Glucosamine (GlucoBright™) and Vitamin B3 (Niacinamide) can be used together effectively for whitening. The product information for GlucoBright™ specifically mentions using it in combination with Niacinamide for enhanced results. Activated Resorcinol™ can also be used alongside Vitamin B3 and N-Acetyl Glucosamine without issues, creating a powerful combination for targeting hyperpigmentation.

Suggestions for Improvement

Your formulation is a good starting point with a strong combination of whitening ingredients. Ensure the pH of your final product is within the optimal range for the active ingredients (e.g., pH 4.5-5.5 for Activated Resorcinol™ and pH 3-7 for GlucoBright™ and Safe-B3™). Using Disodium EDTA helps maintain stability across a wider pH range.

Always perform stability testing on your final formulation to ensure the ingredients remain effective and the product maintains its quality over time and under different conditions.