Serum and Eye Cream Formulation with Peptides and Hyaluronic Acid

ถามโดย: penguin_mom เมื่อ: January 09, 2017 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I would like to create a skin serum and an eye cream using the following ingredients:

  • Double Hyaluron Liquid
  • Argireline
  • Matrixyl or Pep-Coll
  • Safe-B3 (Vitamin B3)
  • Panthenol (Vitamin B5)
  • Mild Preserved Eco
  • Pro Polymer

I previously experienced Argireline clumping like egg whites when mixing it with hyaluronic acid serum. Could you provide a detailed formulation and mixing method for both the serum and the eye cream?

For the eye cream, I would also like to add Encapsulated Caffeine (Slim Coffee).

Additionally, how does purchasing for commercial manufacturing differ from retail purchases?

คำตอบ

Hyaluronic Acid Serum Formulation with Peptides and Eye Cream

Dear Member,

Thank you for your question and additional information. The issue you encountered with Argireline appearing as clumps like egg whites in your hyaluronic acid serum could be due to several factors, such as the mixing order, temperature, or compatibility with other ingredients in your formulation. As the staff initially mentioned, these ingredients should generally be compatible. If you are still experiencing issues, we recommend reviewing your steps and all components again.

Regarding the serum formulation you requested combining Hyaluronic Acid, Argireline, Matrixyl or Pep-Coll, Vitamin B3, and Vitamin B5, the staff has provided a basic formula recommendation. (Please note that Matrixyl and Pep-Coll have similar functions, so it is recommended to choose only one for optimal efficacy in the same formula.)

Basic Skin Serum Formula

  • Double Hyaluron Liquid: 2-5% (Adjust based on desired hydration level)
  • Argireline: 10%
  • Pep-Coll or Matrixyl 3000: 3% (Choose one)
  • Safe-B3 (Vitamin B3): 5% (Helps strengthen skin, reduce redness/dark spots)
  • Panthenol (Vitamin B5): 2% (Provides moisture, strengthens skin barrier)
  • Mild Preserved Eco: 1% (Preservative)
  • Pro Polymer: 1% (Gel maker)
  • Purified Water: Remaining percentage to reach 100%

Serum Mixing Method:

  1. Mix Pro Polymer with purified water and stir until dispersed. Let it sit to form a gel (timing may vary based on Pro Polymer instructions).
  2. Add Double Hyaluron Liquid to the gel mixture and stir until combined.
  3. Add Safe-B3 and Panthenol and stir until dissolved.
  4. Add Argireline and Pep-Coll (or Matrixyl 3000) and stir until fully incorporated.
  5. Add Mild Preserved Eco as the final step and stir to combine.

For the eye cream formulation requesting the above ingredients plus Slim Coffee (Caffeine), you can adapt the serum formula as follows:

Basic Eye Cream Formula

  • Double Hyaluron Liquid: 2-5% (Adjust based on desired hydration level)
  • Argireline: 10%
  • Pep-Coll or Matrixyl 3000: 3% (Choose one)
  • Safe-B3 (Vitamin B3): 5%
  • Panthenol (Vitamin B5): 2%
  • Encapsulated Caffeine (Slim Coffee): Up to 2% (for eye area)
  • Mild Preserved Eco: 1%
  • Pro Polymer: 1-2% (May need to increase Pro Polymer to compensate for thinning caused by Caffeine, which is an electrolyte)
  • Purified Water: Remaining percentage to reach 100%

Eye Cream Mixing Method:

Use a similar mixing method to the serum. Add Encapsulated Caffeine during the step where other active ingredients are added (Step 4). If the formula thins after adding Caffeine, you can gradually add a small amount of Pro Polymer and stir to adjust the consistency.

Important Considerations:

  • The temperature of the formulation when adding Argireline and other peptides should be below 40°C.
  • The pH of the formulation should be within the suitable range for each active ingredient (generally 3.5-6.5 for Argireline, 3-8 for Safe-B3, 3.5-7.0 for Panthenol, 3-9 for Hyaluron).

Regarding your question about purchasing for commercial sale, for large quantities intended for manufacturing, pricing is quoted per kilogram. For retail quantities (not exceeding 500 grams per item), you can order directly through the website.

We hope this information is helpful.

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Panthenol (Vitamin B5, DL-Panthenol, Powder)
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Encapsulated Caffeine (50% Caffeine Active)
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