Serum Formulation for Mature Skin

Based on your initial formula and the staff's recommendations for a serum targeting skin tightening for mature skin (70+), here is the suggested approach:

Your original formula provides hydration and some anti-aging benefits with Hyaluronic Acid, Syn-Ake, Pep-Coll, and Snail Secretion. However, for significant lifting and tightening effects on mature skin, the addition of DMAE is recommended.

DMAE (specifically DMAE Bitartrate, often available as a liquid like DMAE (SkinTight MD™) Liquid) is known for its rapid and effective skin firming properties, which are particularly beneficial for skin with significant wrinkles.

Recommended Formulation Components:

• Water: ~85% (Adjust based on other ingredient percentages)
• Syn-Ake: 3%
• Pep-Coll: 3%
• Snail Secretion: 3%
• Hyaluronic Acid (Standard Molecule): 0.5%
• Hyaluronic Acid (Nano Molecule): 0.5%
• DMAE (SkinTight MD™) Liquid (or equivalent DMAE Bitartrate 10%): 4%
• Triethanolamine 99%: ~3.5% (Used to adjust pH)

• Preservative (e.g., Phenoxyethanol): As per supplier's recommendation (typically 0.5-1%)

• (Note: The percentages for Water and Triethanolamine are approximate and may need slight adjustment based on the specific raw materials and desired final pH.)*

Mixing Instructions:

1. Prepare the Hyaluronic Gel: Start by combining Water with both Hyaluronic Acid (Standard Molecule) and Hyaluronic Acid (Nano Molecule). Mix thoroughly until a gel forms. This can be done by shaking or using a blender as per the Hyaluronic Acid supplier's instructions.
2. Add DMAE: Once the hyaluronic gel is formed, add the DMAE (SkinTight MD™) Liquid to the mixture.
3. Adjust pH: The addition of DMAE will lower the pH. Carefully add Triethanolamine 99% drop by drop, mixing well after each addition, until the pH is in the range of 4.5-5. It's important to add Triethanolamine slowly as the pH can rise quickly, especially when approaching the target range. Aiming for 4.5-5 is sufficient; adjusting higher towards 5-6 requires more patience and smaller additions.
4. Add Heat-Sensitive Ingredients: After the pH has been adjusted and the mixture has cooled (if any heating was involved in dissolving ingredients), add Syn-Ake, Pep-Coll, and Snail Secretion. Mix gently until fully incorporated.
5. Add Preservative: Finally, add your chosen preservative (e.g., Phenoxyethanol) at the recommended usage rate. Mix well.
6. Final Check: Check the final pH and adjust if necessary to be within the stable range for all ingredients (typically 4-6.5 for this type of serum).

Regarding your question about whether the ingredients have different functions: Yes, they do.

• Hyaluronic Acid (Standard and Nano Molecule): Primarily provides hydration at different skin depths.
• Syn-Ake: Works like a mild muscle relaxant to reduce expression lines.
• Pep-Coll: Stimulates collagen production for long-term wrinkle reduction and firmness.
• Snail Secretion: Offers moisturizing, soothing, and regenerative properties.
• DMAE: Provides a noticeable, rapid skin tightening and firming effect.

Combining these ingredients leverages their distinct mechanisms to address multiple signs of aging, including hydration, fine lines, wrinkles, and firmness, which is beneficial for mature skin.