Serum Formulation for Oily Skin: Ingredient Compatibility, Penetration Enhancer, and Texture

Here is a summary of the feedback regarding your proposed serum formulation for oily skin:

1. Compatibility and Adjustments:

   • PE-1 Aqua is not compatible with this formula and should be removed.
   • For oily skin, it is recommended to reduce the concentration of MSH White Absorb™ from 5% to around 3%.
   • The concentration of Pro Polymer™ (Gel Maker) can be reduced from 2% to 1.2-1.5% as this amount is sufficient for thickening.
   • Other ingredients in your list are compatible.
   • You can consider replacing Global Guard™ (preservative) with 1,2-Hexanediol at 3%. 1,2-Hexanediol acts as both a penetration enhancer and a preservative.
   • Adding Ume Extract or Lemon Peel Bioferment is possible and can enhance the results, but the current formula is already effective.

2. Mixing Method:

   • Dissolve all water-soluble ingredients in water first.
   • Add Pro Polymer™ and mix until the gel texture is formed.
   • Add the preservative (e.g., Global Guard™ or 1,2-Hexanediol) last.
   • If there were oil-soluble ingredients, they would typically be added to the gel base after it's formed (though your listed actives appear water-soluble).

3. Mixing Tool:

   • You can mix the formula by hand, but using a machine will make the process easier and potentially yield a smoother result.

4. pH Level:

   • The pH of this formula will be neutral to slightly acidic, which is suitable for the skin.

5. "MSH White 60 days" Note:

   • This note refers to the recommended usage period (60 days) after opening the syringe packaging, not the overall shelf life of the ingredient itself. The actual shelf life can be checked on the website or packaging.

Adjusted Formula (Example based on recommendations):

• GlucoBright™ (N-Acetyl-D Glucosamine) 4%
• MSH White Absorb™ 3% (Reduced for oily skin)
• Rice Vitamin (Inositol, Vitamin B8) 2%
• Licorice Extract (Licochalcone A) 1%
• Pep®-Coll (Palmitoyl Tripeptide-5) 3%
• Acetyl Hexapeptide-8 (Argireline) 10%
• Safe-B3™ (Vitamin B3, Niacinamide) 5%
• 1,2-Hexanediol 3% (Added as penetration enhancer and preservative, replacing PE-1 Aqua and Global Guard)
• Pro Polymer™ (Gel Maker) 1.2-1.5% (Reduced for thickening)
• Water (adjust to 100%)
• (Optional: Add Ume Extract or Lemon Peel Bioferment)