Serum Formulation for Wrinkle Reduction: Mixing, Thickening, and pH

Asked by: saifon_ae On: August 05, 2013 Product Type: Cosmetics

Question

I am developing a serum formulation for reducing forehead and smile lines. The ingredients I plan to use are:

  • Argireline 10%
  • Pep®-Coll 5%
  • Homeostatine™ 5%
  • Aloe Vera Extract 3%

I intend to mix all these ingredients in distilled water. Will this work? How can I achieve a thicker, gel-like texture? Do I need to test or adjust the pH?

Answer

Serum Formulation for Wrinkle Reduction

Regarding your serum formulation for reducing forehead and smile lines using Argireline 10%, Pep®-Coll 5%, Homeostatine™ 5%, and Aloe Vera Extract 3%:

  1. Mixing and Thickening:

    • Yes, you can mix all the ingredients in distilled water. However, as the staff mentioned, this will result in a liquid consistency.
    • To achieve a thicker, gel-like texture, you will need to add a thickener such as Pro Polymer.
    • You can start by adding Pro Polymer at a concentration of 0.5% and increase it gradually until you reach your desired viscosity.
  2. pH Testing:

    • Based on the ingredients in your formula, pH testing is not strictly necessary.
    • The formulation is expected to have a slightly acidic pH (around 5-6), which is well-suited for facial skin.

Ingredient Functions:

  • Argireline (Acetyl Hexapeptide-8) is a peptide known for its ability to help reduce the appearance of wrinkles caused by muscle movement, particularly on the forehead and around the eyes.
  • Pep®-Coll (Palmitoyl tripeptide-5) is a peptide designed to stimulate the skin's natural collagen production, helping to reduce wrinkles.
  • Aloe Vera Extract provides skin conditioning, helps reduce irritation, and moisturizes the skin.