Serum Formulation: Ingredients and Mixing Guide
คำถาม
Could you please provide the formulation/mixing instructions for a serum containing the following active ingredients?
- Bifida Ferment Lysate
- Tocopheryl Acetate
- Glycine Soja (Soybean) Seed Extract (Soy Extract)
- Olea Europaea (Olive) Fruit Extract
- Triticum Vulgare (Wheat Bran) Extract
- Polygonum Cuspidatum Root Extract
- Vitis Vinifera (Grape) Seed Extract
- Selaginella Tamariscina (Spike Moss) Extract
- Cola Nitida (Kola) Nut Extract
- Humulus Lupulus (Hops) Extract
- Nordihydroguaiaretic Acid
- Citri Reticulate Peel Extract
- Punica Granatum (Pomegranate) Juice Extract (Pomegranate Seed Oil)
- Cholesterol
- Sea Whip Extract
- Sodium Hyaluronate
- Micrococcus Lysate
- caffeine
- Alteromonas Ferment Extract
- Sodium RNA
- Pantethine (Panthenol)
- Arabidopsis Thaliana Extract
- Yeast Extract
- Ethylbisiminomethylguaiacol Manganese Chloride
- Anthemis Nobilis (Chamomile)
- Linoleic Acid (LipidSoft F)
- Hydrogenated Lecithin
- Rosmarinus Officinalis (Rosemary) Extract (Rosemary Extract)
- Linolenic Acid
- Lauryldimonium Hydroxypropyl Hydrolyzed Soy Protein
คำตอบ
Serum Formula Analysis and Mixing Guide
This serum formula is designed to provide comprehensive skin benefits, focusing on hydration, repair, antioxidant protection, and soothing. It features a blend of fermented ingredients, plant extracts, vitamins, and silicones.
Key Ingredients and Their Benefits:
Repair and Barrier Support:
- Bifida Ferment Lysate: Known for its ability to help the skin repair DNA damage, particularly from UV exposure, and support the skin barrier.
- Yeast Extract: Contains oligopeptides that promote skin cell turnover, leading to clearer, more flexible skin and reduced wrinkles. It can also help brighten the skin and reduce dark spots.
- Hydrolyzed Soy Protein: Can help improve skin and hair moisture absorption.
- Hydrogenated Lecithin (Phospholipid): Acts as a natural emulsifier and helps form liposomes, enhancing ingredient penetration. It also moisturizes the skin, supports the barrier, and reduces irritation.
Hydration and Moisture:
- Hyaluronic Acid: A powerful humectant that attracts and retains moisture, improving skin hydration and reducing the appearance of wrinkles.
- Butylene Glycol, Glycerin, Methyl Gluceth-20: Common humectants that draw moisture into the skin.
- Cholesterol: An essential component of the skin's natural lipid barrier, helping to restore dry skin and improve moisture.
- Lecithin: A natural emulsifier with moisturizing properties.
Antioxidant and Soothing Properties:
- Tocopheryl Acetate (Vitamin E): A stable form of Vitamin E that provides antioxidant protection against free radicals.
- Soy Extract: Contains isoflavones like Genistein, which offer antioxidant benefits, stimulate collagen production, moisturize the skin, and can help inhibit melanin production and age spots.
- Olive Extract: Rich in antioxidants like Hydroxytyrosol and Oleuropein, offering protection against free radicals and having antibacterial properties.
- Grape Seed Extract: Contains potent antioxidants (OPCs) that help protect the skin.
- Chamomile Extract: Known for its soothing and anti-inflammatory properties, helping to reduce skin irritation and redness due to its Apigenin content.
- Pomegranate Seed Oil: Rich in antioxidants and fatty acids, helping to fight free radicals, reduce wrinkles, and prevent dryness.
- Other Extracts: Triticum Vulgare (Wheat Bran) Extract, Polygonum Cuspidatum Root Extract, Vitis Vinifera (Grape) Seed Extract, Selaginella Tamariscina (Spike Moss) Extract, Cola Nitida (Kola) Nut Extract, Humulus Lupulus (Hops) Extract, Sea Whip Extract, Rosmarinus Officinalis (Rosemary) Extract contribute various antioxidant, soothing, or conditioning benefits.
- Caffeine: Can stimulate microcirculation, potentially helping with puffiness and dark circles, and has antioxidant effects.
Texture and Feel:
- Cyclopentasiloxane, Dimethicone, Bis-PEG-18 Methyl Ether Dimethyl Silane, Peg-9 Dimethicone, Simethicone, Polymethylsilsesquioxane: Silicones that provide a smooth, non-greasy feel, improve spreadability, and can offer a soft-focus or blurring effect (Polymethylsilsesquioxane, Silica, Titanium Dioxide).
- Silica, Titanium Dioxide: Can contribute to texture, oil absorption, and potentially a matte or blurring effect.
- Xanthan Gum, Carbomer: Thickeners used to create the serum's gel texture and viscosity.
- Caprylic/capric triglyceride: An emollient derived from coconut oil, providing a light, non-greasy feel.
Stabilizers and Preservatives:
- Disodium EDTA: A chelating agent that helps stabilize the formula by binding to metal ions.
- Potassium Sulfate, Tromethamine: Likely used for pH adjustment or buffering.
- BHT: An antioxidant used to prevent oxidation of oils.
- Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol: Preservatives used to protect the formula from microbial growth.
General Mixing Guide:
This is a complex formula, likely an emulsion (oil-in-water or water-in-oil) or a complex gel-serum with both water and oil phases. A general mixing approach would involve combining ingredients based on their solubility and heat sensitivity.
- Water Phase: Combine water-soluble ingredients like Water, Butylene Glycol, Glycerin, Methyl Gluceth-20, Hyaluronic Acid, Bifida Ferment Lysate, Yeast Extract, Hydrolyzed Soy Protein, Sodium RNA, Pantethine, Potassium Sulfate, Tromethamine, Disodium EDTA, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol, Caramel, and most plant extracts (Olive Extract, Grape Seed Extract, Chamomile Extract, etc.). Thickeners like Xanthan Gum and Carbomer would be dispersed in the water phase and then neutralized (for Carbomer) to form the gel. Some extracts might need to be added after cooling if they are heat sensitive (e.g., Olive Extract, Grape Seed Extract, Yeast Extract, Chamomile Extract).
- Oil/Silicone Phase: Combine oil-soluble and silicone-based ingredients like Cyclopentasiloxane, Bis-PEG-18 Methyl Ether Dimethyl Silane, PEG-60 Hydrogenated Castor Oil, Tocopheryl Acetate, Glycine Soja Seed Extract (if oil-soluble form is used), Olea Europaea (Olive) Fruit Extract (if oil form is used, though extract is usually water-soluble), Triticum Vulgare (Wheat Bran) Extract (if oil form), Polygonum Cuspidatum Root Extract (if oil form), Vitis Vinifera (Grape) Seed Extract (if oil form), Selaginella Tamariscina Extract (if oil form), Cola Nitida Nut Extract (if oil form), Humulus Lupulus Extract (if oil form), Ascorbyl Tocopheryl Maleate, Nordihydroguaiaretic Acid, Citri Reticulate Peel Extract (if oil form), Pomegranate Seed Oil, Cholesterol, Sea Whip Extract (if oil form), Micrococcus Lysate (if oil form), Caffeine (if oil-soluble form, though extract is water-soluble), Alteromonas Ferment Extract (if oil form), Arabidopsis Thaliana Extract (if oil form), Ethylbisiminomethylguaiacol Manganese Chloride (if oil form), Linoleic Acid, Lecithin, Hydrogenated Lecithin, Rosmarinus Officinalis Extract (if oil form), Linolenic Acid, Lauryldimonium Hydroxypropyl Hydrolyzed Soy Protein (if oil form), Polymethylsilsesquioxane, Dimethicone, Peg-9 Dimethicone, Simethicone, Caprylic/capric triglyceride, BHT, Titanium Dioxide, Silica. Cholesterol requires high heat (above 150°C) to dissolve in the oil phase before combining with other ingredients. Hydrogenated Lecithin should be dispersed at room temperature.
- Emulsification/Combination: If it's an emulsion, the heated oil phase (containing dissolved Cholesterol and other heat-stable oils/silicones) would be slowly added to the heated water phase while mixing vigorously with an emulsifier (like PEG-60 Hydrogenated Castor Oil, Lecithin, Hydrogenated Lecithin, or others not explicitly listed but implied by the formula's nature). If it's a gel-serum, the oil/silicone phase might be dispersed into the gelled water phase.
- Cooling and Adding Sensitive Ingredients: Allow the mixture to cool. Add heat-sensitive ingredients like many plant extracts, vitamins (some forms), and preservatives (Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol, Potassium Sorbate). Adjust pH if necessary.
- Final Mixing: Mix thoroughly to ensure homogeneity.
Important Considerations for Mixing:
- Always follow specific instructions for each raw material regarding solubility, temperature limits, and pH range.
- Ensure proper dispersion of powders (like Carbomer, Xanthan Gum, Silica, Titanium Dioxide, Cholesterol, Hydrolyzed Soy Protein, Hydrogenated Lecithin, Lecithin) to avoid clumping.
- Cholesterol requires very high heat to dissolve in oil, which must be done carefully before combining with other ingredients.
- Hydrogenated Lecithin and Lecithin have specific dispersion requirements (room temperature for Hydrogenated Lecithin, use heat for Lecithin).
- Maintain the correct pH range for optimal stability and efficacy of ingredients like Carbomer (neutralized pH 6-7), Soy Extract (pH 5-7), Olive Extract (pH 4.0-6.5), Grape Seed Extract (avoid heat > 40°C), Yeast Extract (pH 4.0-6.5, avoid heat > 40°C), Chamomile Extract (avoid heat > 40°C).
- Use appropriate mixing equipment (e.g., high-shear mixer for emulsification, propeller mixer for general mixing).
- Perform a challenge test to ensure the preservative system is effective for the final formula.
ผลิตภัณฑ์ที่เกี่ยวข้องที่กล่าวถึง
Vitamin E (Tocopheryl Acetate)
Hyaluronic Acid (Small Molecule, 8-20K Daltons)
Panthenol (Vitamin B5, DL-Panthenol, Powder)
Phenoxyethanol (Extra Pure)
Fractionated Coconut Oil
Disodium EDTA
Xanthan Gum (clear gel type, smooth texture)
Soy Extract (Isoflavones / Genistein)
Butylene Glycol
Dimethicone (Light/50, Low-Odor)
MatteSilica 5™ (5 Micron)
Cholesterol (95%, NF, Fine Powder)
Ethylhexylglycerin
Carbomer 940 (EasyDisperse™, France)
Olive Extract (Hydroxytyrosol , Oleuropein)
Grape Seed Extract (Proanthocyanidins)
Yeast Resurface
Chamomile Extract (Apigenin)
Phospholipid