Serum Formulation with Multiple Actives in Aloe Gel Base

Based on the staff's response, here's a summary regarding the effectiveness of all-in-one products and your specific formulation:

Effectiveness of All-in-One Products:
Achieving high effectiveness for multiple concerns (lifting, anti-wrinkle, whitening, sun protection) in a single product is complex. The staff highlighted key factors that influence ingredient compatibility and performance:

• Optimal Conditions: Each ingredient works best under specific conditions (e.g., pH levels). Combining ingredients with vastly different optimal conditions can reduce their effectiveness.
• Solubility: Ingredients must be compatible with the product base (water-based, oil-based).
• Mechanism of Action: Combining ingredients with similar mechanisms might not provide additive benefits.
• Concentration: The total concentration of active ingredients must allow for a suitable product texture and base (sufficient water content).

While it's possible to combine multiple ingredients, optimizing the environment for all of them simultaneously can be challenging. This is often why products focused on a single concern or a few compatible concerns can achieve higher efficacy in those specific areas compared to a broad "all-in-one" product.

Regarding Your Specific Formulation (Aloe gel + Dmae 4% + Pepha®-Tight 3% + Alpha-Arbutin 2% + Leuphasyl 8% + SNAP-8 8%):

• Ingredient Compatibility: The staff confirmed that the ingredients you listed can work together without major issues, specifically noting that Leuphasyl and SNAP-8 have different mechanisms and can be combined.
• Water Content: The staff calculated the total active ingredient percentage to be 26.99%, meaning the water content is 73.01%. This is well within the recommended range of at least 30-40%.
• Price: I cannot calculate the exact price for custom formulations. The staff directed you to the product page for the Aloe Vera Gel base, where you can select the ingredients and quantities to get an automatic price calculation.
• Optimal pH: The staff mentioned pH as a crucial factor for ingredient effectiveness but did not provide the optimal pH range for each specific ingredient in your formulation or the resulting pH of the mixture. Therefore, I cannot confirm if the pH of your proposed formulation (or the split formulations) is optimal for maximum effectiveness based on the information provided.

The staff also suggested considering adding natural extracts like Green Tea EGCG or Gotu Kola and reminded you to store the mixture in a cool place due to the lack of preservatives.