Skincare Formulation Advice: Lifting, Wrinkles, Melasma, Freckles
Question
I have combination skin with concerns about melasma, freckles, wrinkles, and loss of firmness. I have developed two skincare formulations and would like expert advice on how to improve them.
Formula 1: Lifting, Anti-wrinkle
My current formulation includes:
- Acetyl Hexapeptide-8 (Argireline) 10%
- Matrixyl 3000 5%
- Lift-Now™
- Repair Activator™ 15%
- Copper Peptide (GHK-Cu) 3%
- Full & Lift™ 5%
- Coenzyme Q10 Extra 1%
- Centella Asiatica Extract (Madecassoside 7.7%) 2%
- Pro Polymer™ (Gel Maker) 2%
- Phenoxyethanol (Optiphen) 1% (or Phenoxyethanol SA 1%)
- DI water to 100%
Please advise on potential adjustments to enhance lifting and wrinkle reduction, improve texture (avoid lumpiness), and consider suitability for day/night use.
Formula 2: Melasma/Freckle Reduction, Exfoliation
My current formulation includes:
- Pumpkin Renew™ 5%
- Azelaic Acid (Liquid Azelaic™) 10%
- Vitamin B3, Niacinamide (Safe-B3™) 2%
- N-Acetyl-D glucosamine (GlucoBright™) 4%
- Phenoxyethanol (Optiphen) 1%
- DI water
Please advise on the suitability of ingredients like DMAE for this purpose, recommend a suitable product texture (gel or lotion), and suggest mixing steps, especially considering the high concentration of Azelaic Acid.
Answer
Here is a summary of the staff's advice regarding your two skincare formulations for combination skin with melasma, freckles, wrinkles, and loss of firmness:
Formula 1: Lifting, Anti-wrinkle
Adjustments:
- Reduce Repair Activator™ from 15% to 10%.
- Add DMAE (SkinTight MD™) Liquid 5-7% for enhanced lifting and wrinkle reduction.
- Add Safe-B3™ 3% to strengthen the skin.
- Lift-Now™ provides temporary tightening and is best for daytime use. For nighttime or if uncomfortable, consider a lower percentage (1-2%) or omitting it.
- Reduce Pro Polymer™ (Gel Maker) from 2% to no more than 1.5% to prevent lumpiness.
Revised formula suggested by staff:
- Acetyl Hexapeptide-8 (Argireline) 10%
- Matrixyl 3000 5%
- Lift-Now™ (use sparingly or omit)
- Repair Activator™ 10%
- Copper Peptide (GHK-Cu) 3%
- Full & Lift™ 5%
- Coenzyme Q10 Extra 1%
- Centella Asiatica Extract (Madecassoside 7.7%) 2%
- Pro Polymer™ (Gel Maker) 1.5%
- Phenoxyethanol (Optiphen) 1% (or Phenoxyethanol SA 1% for sensitive skin)
- Safe-B3™ 3%
- DMAE (SkinTight MD™) Liquid 5%
- DI water to 100%
Mixing Steps:
- Combine ingredients 1, 2, 4, 5, 10, 11, 12 with DI water (13) and mix until clear.
- Add Pro Polymer™ (9) and mix/blend until a gel forms.
- Warm Full & Lift™ (6) to 60°C, mix until smooth, then add to the gel and mix.
- Add the remaining ingredients (7, 8) to the gel and mix.
pH Adjustment:
- The staff's advice did not include instructions for pH adjustment for this formula.
Formula 2: Melasma/Freckle Reduction, Exfoliation
Adjustments:
- DMAE (SkinTight MD™) Liquid was recommended for Formula 1 as it focuses on lifting/wrinkles, not melasma/exfoliation.
- Relevant ingredients from your list for this purpose are Pumpkin Renew™ 5%, Azelaic Acid (Liquid Azelaic™) 10%, Vitamin B3, Niacinamide (Safe-B3™) 2%, N-Acetyl-D glucosamine (GlucoBright™) 4%, Phenoxyethanol (Optiphen) 1%, and DI water.
- For enhanced whitening/melasma reduction, consider adding Activated Resorcinol 1% (must be dissolved in oil or LipidSoft before adding to the formula).
Suitable Texture (Gel or Lotion):
- Due to the high concentration of Azelaic Acid (an electrolyte), the staff recommended a gel texture using Pro Polymer™ at 1.5-2.0%. The electrolyte effect weakens the gel structure, requiring a higher amount of gel maker.
Mixing Steps (for Gel):
- Combine all water-soluble ingredients (Pumpkin Renew™, Azelaic Acid, Panthenol, Safe-B3™, GlucoBright™, Phenoxyethanol, DI water) first.
- Then add Pro Polymer™ and mix/blend until a gel forms. This may take longer than usual due to the electrolyte effect of Azelaic Acid.
pH Adjustment:
- The staff's advice did not include instructions for pH adjustment for this formula.
Related Products Mentioned
Acetyl Hexapeptide-8 (eq Argireline)
Pal-GHK, Pal-GQPR (eq Matrixyl 3000)
Safe-B3™ (Vitamin B3, Niacinamide)
GlucoBright™ (Acetyl Glucosamine)
Phenoxyethanol (Extra Pure)
Pro Polymer™ (Gel Maker)
Lift-Now™
Coenzyme Q10 Extra
DMAE (SkinTight MD™) Liquid
Phenoxyethanol SA (eq. Optiphen Plus)