Solubility and Formulation of Activated Resorcinol™ and NanoRes™
Question
Regarding the solubility of Activated Resorcinol™ (4-Butyl Resorcinol):
- Is it soluble in oils other than LipidSoft/LipidSoft CC, such as Olive Oil, Grape Seed Oil, or Fractionated Coconut Oil?
- If used in a pure oil blend (dissolved in oil and applied directly), is a preservative like Phenoxyethanol necessary?
- How does the solubility and formulation differ for NanoRes™ (another form of 4-Butyl Resorcinol)?
Answer
Solubility of 4-Butyl Resorcinol
Regarding the solubility of Activated Resorcinol™ (4-Butyl Resorcinol), it is soluble in oil. This means you can dissolve it in various oils, including the ones you mentioned like Olive Oil, Grape Seed Oil, or Fractionated Coconut Oil, not just LipidSoft or LipidSoft CC.
While Activated Resorcinol™ can be dissolved in oil, it is generally recommended to formulate it into a cream or lotion base for better stability, absorption into the skin, and a more pleasant texture. A typical cream or lotion formulation would involve mixing the oil phase (containing the dissolved Activated Resorcinol™) with a water phase using an emulsifier.
Regarding the preservative Phenoxyethanol, it is water-soluble. If you are making a simple oil blend (dissolving Activated Resorcinol™ in oil and applying directly), you generally do not need a preservative like Phenoxyethanol, as preservatives are primarily needed in formulations containing a water phase to prevent microbial growth. If you plan to make a cream or lotion which contains water, then Phenoxyethanol can be added to the water phase of your formulation at the recommended usage rate (typically 0.5-1.0%).
There is also another form of 4-Butyl Resorcinol called NanoRes™ which is encapsulated in liposomes and is water-soluble, making it suitable for water-based formulations like serums or toners without needing an oil phase for dissolution.
In summary, Activated Resorcinol™ dissolves in oil and can be used with oils like Olive Oil, Grape Seed Oil, or Fractionated Coconut Oil. However, for a stable and effective skin whitening product, formulating it into a cream or lotion is advisable. Phenoxyethanol is a water-soluble preservative suitable for formulations containing water, not pure oil blends.
Related Products Mentioned
Olive Oil (Extra Virgin)
Phenoxyethanol (Extra Pure)
Fractionated Coconut Oil
LipidSoft™ CC (Cetyl Ethylhexanoate)