Solubility Issue with B3-Boost (Picolinamide) in Butylene Glycol

ถามโดย: ไม่ระบุชื่อ เมื่อ: May 24, 2025 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

I am trying to dissolve B3-Boost (Picolinamide) at a concentration of 5% in 12% Butylene Glycol and encountered precipitation/incomplete dissolution. Why is this happening?

คำตอบ

Solubility Issue with B3-Boost (Picolinamide)

Regarding the issue of dissolving B3-Boost (Picolinamide) at a concentration of 5% in 12% Butylene Glycol resulting in precipitation, the information available indicates that B3-Boost (Picolinamide) is indeed soluble in glycols such as Butylene Glycol.

However, the recommended usage rate for B3-Boost (Picolinamide) is typically between 0.1% and 1%. Using a concentration as high as 5% significantly exceeds this recommended range.

It is highly probable that the concentration of 5% B3-Boost exceeds its solubility limit in 12% Butylene Glycol, leading to the observed precipitation and incomplete dissolution. To achieve complete dissolution, it is recommended to reduce the concentration of B3-Boost (Picolinamide) to within the recommended usage range of 0.1-1%.

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B3-Boost™ (Picolinamide)
B3-Boost™ (Picolinamide)
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