Solubility of Activated Resorcinol and MSH White in Cream Formulation

Question

I am creating a cream formulation. I understand that Activated Resorcinol 1% needs to be dissolved in the oil phase, specifically using LipidSoft at a ratio of 2% (2% LipidSoft for 1% Activated Resorcinol). Is this correct? My formulation involves mixing oil-soluble ingredients (including Activated Resorcinol and MSH White) in phase A (Avocado Oil + LipidSoft), water-soluble ingredients in phase B, combining A+B, and then adding preservative/EDTA. Please confirm the dissolution process and ratio, and advise on potential issues like Vitamin B6 affecting viscosity.

MySkinRecipes Expert · Accepted Answer

Yes, your understanding is correct. Activated Resorcinol is oil-soluble and needs to be dissolved in the oil phase of your formulation, such as using a LipidSoft type. Using LipidSoft at a ratio of 2% for 1% Activated Resorcinol is a suitable amount to ensure the Activated Resorcinol dissolves completely.

It's important to ensure both Activated Resorcinol and MSH White are fully dissolved in the oil phase (Avocado Oil + LipidSoft) using heat (around 80°C as suggested for MSH White) before combining with the water phase. The mixing steps you outlined previously (mixing oil-soluble ingredients in phase A, water-soluble in phase B, combining A+B, then adding preservative/EDTA) are appropriate for creating a cream emulsion with these ingredients.

Remember that Vitamin B6 can affect the viscosity of the cream, as mentioned before. You might need to adjust the amount of Light Cream Maker to achieve your desired texture after combining the phases.