Solubility of L-Ascorbic Acid in Glycols

Regarding the solubility of L-ascorbic acid in glycols such as Butylene Glycol and Ethoxydiglycol, based on general information and the discussion, the typical solubility in the glycol group is around 5%.

You observed a serum containing 12% L-ascorbic acid dissolved in Butylene Glycol. It is possible to achieve higher concentrations than the typical solubility limit in specific formulations. This could be due to the presence of other ingredients or specific formulation techniques that are not always fully disclosed in commercial products, as mentioned in the forum replies.

While L-ascorbic acid is soluble in water, it is highly unstable in aqueous solutions. It is often used in anhydrous (water-free) formulations, where it can be dissolved or dispersed in solvents like glycols to maintain stability.

For typical formulations, a solubility of around 5% in glycols is generally expected. Achieving significantly higher concentrations may require specialized knowledge or additional components in the formula.