Stability and Concentration of Vitamin C Derivatives (Tetrahexyldecyl Ascorbate, Ethyl Ascorbic Acid) in Serum

Asked by: i.am.abundant8 On: October 29, 2016 Product Type: Cosmetics

Question

Regarding Vitamin C derivatives:

  1. For Tetrahexyldecyl Ascorbate:
    • If mixed with Vitamin E and Ferulic Acid, will it help increase stability?
    • If produced as a serum and stored at room temperature, how long will it remain stable?
  2. For Ethyl Ascorbic Acid:
    • Can it be used at concentrations higher than 5%? Specifically, if used at 10-15%, will the effectiveness increase?
    • What is the maximum percentage of this Vitamin C derivative that the skin can absorb?

Answer

Regarding your questions about Vitamin C derivatives:

  1. Tetrahexyldecyl Ascorbate (ID 499):

    • We do not have specific information on whether combining it with Vitamin E (ID 65) and Ferulic Acid (ID 131) will further increase its stability.
    • However, Tetrahexyldecyl Ascorbate is inherently more stable than L-Ascorbic Acid (ID 133/134). For a serum formulation stored at room temperature, it is relatively stable, even at temperatures around 30-35°C. To maintain stability, it is crucial to protect the product from sun and heat exposure. Using opaque bottles (like ceramic) and airless pumps is highly recommended.
  2. Ethyl Ascorbic Acid (ID 833):

    • Yes, it can be used at concentrations higher than 5%, such as 10-15%.
    • However, based on our experience, using it at 10-15% did not show a noticeable increase in effectiveness compared to using it at 5%. This observation is similar to testing different concentrations of AA2G (ID 265).
    • The provided information does not specify the maximum percentage of Ethyl Ascorbic Acid that the skin can absorb.