Stability of Alpha Arbutin and Deoxyarbutin: Preventing Hydroquinone Formation

ถามโดย: gashbell_7918 เมื่อ: October 24, 2018 ประเภทผลิตภัณฑ์: เครื่องสำอาง

คำถาม

Is it true that Arbutin group ingredients like Alpha Arbutin and Deoxyarbutin can break down into Hydroquinone? If so, how can this be prevented in cosmetic formulations?

คำตอบ

Deoxyarbutin and Hydroquinone Formation

Yes, it is true that Deoxyarbutin (D-Arbutin) can have stability issues related to heat, which can lead to its breakdown into Hydroquinone. This is a known characteristic of Deoxyarbutin.

Other substances in the Arbutin group, such as Alpha Arbutin, can also break down into Hydroquinone, particularly in formulations with a high pH (above 8).

To maintain the stability of these ingredients and prevent the formation of Hydroquinone:

  • For Deoxyarbutin (D-Arbutin):

    • Avoid heating above 60°C during the mixing process. If heating is necessary, minimize the exposure time.
    • Maintain the formula's pH between 5.0 and 5.8 for optimal stability.
    • Consider using Vitamin E Acetate at 0.1% and ActiveProtecTM OX at 0.6% in the formula to help enhance stability and prevent discoloration.
  • For Alpha Arbutin (including Alpha Arbutin (Switzerland), Alpha Arbutin (China, Powder, Enzymatic Synthesis), and Alpha Arbutin (China, Crystal Form)):

    • Mix into the final product when the temperature is below 30°C.
    • Ensure the formula's pH is between 3.5 and 6.5. Avoid formulations with a pH higher than 8.
    • Using ActiveProtecTM OX at 0.6% can help prevent formula discoloration.

By following these guidelines, you can help ensure the stability and safety of cosmetic products containing Deoxyarbutin or Alpha Arbutin.

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