Technical Details and Formulation Guidelines for O₂-Complex™ (Perfluorodecalin) Oxygen Carrier
Asked by: Anonymous
On: October 29, 2025
Product Type:
Cosmetics
Question
What are the essential details regarding O₂-Complex™ (Pure Perfluorodecalin), a perfluorocarbon liquid utilized for the oxygen donor/carrier concept in cosmetics? Please provide the following information, including specific formulation and handling guidelines:
- INCI Name
- Function, Concept (e.g., 'Oxygen Net' skincare concept)
- Recommended Usage and Usage Rate (0.5–5%)
- Specifications and Characteristics (e.g., clear, colorless, high density, chemically inert)
- Safety and Compatibility (especially regarding water/oil incompatibility)
Formulation and Mixing Guidelines:
- How must it be dispersed (e.g., PFD nanoemulsions or capsule systems)?
- Optional Oxygenation process (cooling to 5–10°C, spurting medical-grade O₂ for 15–30 minutes per liter).
- Temperature and Shear Control requirements (control temperature to ≤40°C, avoid high shear/vacuum).
- Specific Packaging requirements (filling under O₂, minimizing air gaps, using high-gas barrier packaging).
- Monitoring methods (Oxygen Meter/Gas Analyzer).
Answer
O₂-Complex™ (Pure Perfluorodecalin) Product Details
O₂-Complex™ is a chemically inert perfluorocarbon liquid used to condition the skin and act as an oxygen carrier.
| Category | Details |
|---|---|
| INCI Name | Perfluorodecalin |
| Function/Concept | Skin conditioning agent and oxygen carrier/donor. It is highly soluble in gases (especially oxygen and carbon dioxide). Suitable for the 'Oxygen Net' skincare concept and post-procedure care. |
| Usage | Serums, creams or lotions, masks, and post-procedure soothing products. |
| Usage Rate | 0.5–5% |
| Specifications/Characteristics | Clear, colorless, high density, and chemically inert liquid. |
| Compatibility | Incompatible with water and common oils. It must be emulsified or encapsulated before being mixed into the formula. |
| Safety | The product is chemically inert. Effectiveness depends on the amount of oxygen contained, droplet size, packaging barriers, and packaging conditions. |
Formulation and Mixing Guidelines
The effectiveness of O₂-Complex™ relies heavily on proper formulation and handling to maximize and maintain its oxygen content.
- Dispersion: Must be used as a finely dispersed phase in emulsions (PFD nanoemulsions) or capsule systems to ensure miscibility with water/oil phases.
- Oxygenation (Optional):
- Cool the product to 5–10°C.
- Spurt medical-grade fine-foaming O₂ for 15–30 minutes per liter.
- Temperature and Shear Control:
- Control temperature to ≤40°C.
- Avoid high shear forces, which can cause oxygen to escape.
- Avoid vacuum aspiration after oxygen filling.
- Packaging:
- Fill under O₂ or evacuate voids.
- Minimize air gaps.
- Use high-gas barrier packaging (e.g., foil/laminate/outlet) to maintain O₂ content.
- Monitoring: Monitor the oxygen concentration using an Oxygen Meter (Gas Analyzer) or an optical oxygen probe for non-water based liquids.
Related Products Mentioned
O2-Complex™ (Pure Perfluorodecalin)
Cosmetics