Using CysWhite™ (Cysteamine HCL) in Skincare

CysWhite™ (Cysteamine HCL) is recognized as a potent skin whitening ingredient, even more effective than hydroquinone according to some research, particularly for addressing blemishes. However, it is known for having a strong odor and requires careful application.

Application Method

1. Apply in the evening: Use the cream in the evening.
2. Apply to dry skin: It is crucial to apply the cream to completely dry skin. If you have washed your face, wait for about 1 hour before application. Applying to damp or wet skin can increase absorption and potentially lead to irritation or burning, similar to the precautions needed when using Tretinoin.
3. Leave on for a limited time: Apply the cream and leave it on for 10-15 minutes. Do not leave it on for longer than 15 minutes to minimize the risk of irritation or peeling.
4. Cleanse after use: After the recommended time, cleanse your face thoroughly using your regular cleansing routine (cleansing followed by cleanser).
5. Follow with regular skincare: Continue with your usual skincare routine.

Usage Frequency

• Initial Phase (First 16 weeks): Apply once daily every evening.
• Maintenance Phase (After 16 weeks): Reduce application to twice per week, once each evening.

Potential Side Effects

• In the first few days of use, you might experience a mild warming sensation or slight redness, which should subside within 30 minutes and improve with subsequent applications.
• To prevent side effects like peeling or burning, adhere strictly to the 10-15 minute application time, apply only to dry skin, and ensure adequate moisturization. Using a good moisturizer is important.

Important Considerations

• Avoid other exfoliating/whitening products: While using CysWhite™, it's generally recommended to avoid other strong exfoliating agents or whitening products to prevent skin irritation.
• Combining with TXA: For those with resilient skin who tolerate the treatment well and desire faster results, combining with Tranexamic Acid (TXA) may offer enhanced benefits. Products like Tranexamic Acid (Trans-White™), TXC™ (Cetyl Tranexamate HCl), or Nano-TXA™ (Tranexamic Acid Nano Emulsion, Penetration Base) are available.
• Sun Protection: Daily use of sunscreen with sufficient quantity (like the two-finger rule) is absolutely essential, especially when using potent whitening ingredients. Reapply sunscreen every 2-3 hours when exposed to sunlight.
• Contraindication: CysWhite™ should not be used by individuals who are pregnant, breastfeeding, or planning to become pregnant.
• Odor: CysWhite™ has a characteristic strong smell. Adding an odor absorber like Odor-Kill (1-2%) to a formulation containing CysWhite™ is recommended to help mitigate this issue.
• Formulation Stability: CysWhite™ has low stability when dissolved in water. For long shelf-life formulations, an anhydrous (water-free) base is recommended.

Thank you again for sharing your valuable insights on using CysWhite™ cream!