Using Copper Peptide (GHK-Cu) & Pep-Coll After Derma Point: Duration, Zinc PCA, pH, and Ingredient Compatibility
Question
I am using a formula containing Copper Peptide (GHK-Cu) and Pep®-Coll after a Derma Point procedure. I have a few questions based on my experience and observations:
- How long should I continue using this formula? I understand that GHK-Cu is effective when the skin has wounds, but my visible wounds have healed, leaving only redness. Should I still continue using it?
- Zinc PCA was recommended for the formula, but I didn't include it because I thought Zinc PCA primarily reduces facial oil. After the Derma Point procedure, my face became dry and peeled on the 5th day. Is it suitable to add Zinc PCA now, or are there other ingredients I could add that won't interfere with the main active ingredients?
- I initially planned to adjust the pH to 5.5, but I hesitated because I learned that Cu++ should not be used with EDTA. The current pH is 6.12. I was considering adding Citric Acid or Lactic Acid to adjust the pH, but I realized they also have chelating properties. Based on my understanding of the structure of EDTA and its ability to chelate Cu++, I suspect Citric Acid and Lactic Acid might also interfere. Could you please provide a clear scientific explanation to confirm if my concern about chelating agents interfering with Cu++ is valid?
- Could the staff please confirm the import status and future availability of Copper Peptide (GHK-Cu) or alternative ingredients? I plan to purchase derma stamp equipment and anesthetic for personal use and need to know if I should stock up on GHK-Cu if it will be discontinued.
Answer
Review of Copper Peptide (GHK-Cu) + Pep-Coll after Derma Point
Thank you for sharing your experience with the formula containing Copper Peptide (GHK-Cu) and Pep®-Coll after your derma point procedure. It's great to hear you're seeing positive results with faster healing and smoother skin.
Here are the answers to your questions, based on the information provided:
How long should I continue using this formula?
- You can continue using the formula. Although the visible wounds have closed, the redness indicates that your skin is still undergoing a repair process beneath the surface. Copper Peptide (GHK-Cu) is most effective during this active skin repair phase. The staff recommends using the formula for a full month for optimal results.
Why is Zinc PCA recommended, and is it suitable given my dry skin?
- Zinc PCA is recommended because it has wound-healing properties and helps accelerate the recovery of skin lesions, such as acne scars or the micro-wounds created by derma point/dermaroller. While Zinc PCA can also help control oil, its primary benefit in this context is promoting healing.
- Given that your skin is dry and peeling after the procedure, adding Zinc PCA might potentially increase dryness for some individuals. However, its healing benefits could still be valuable. If dryness is a significant concern, you might consider focusing on hydrating ingredients or using a separate hydrating product alongside your peptide serum, rather than adding Zinc PCA to this specific formula at this time.
Should I adjust the pH to 5.5? Are Citric Acid and Lactic Acid chelating agents that interfere with Cu++?
- Your concern is valid. As confirmed by C7, ingredients like Citric Acid, Lactic Acid (AHAs), and EDTA are indeed chelating agents. They can bind to metal ions like Cu++ (copper ions) found in Copper Peptide (GHK-Cu).
- This binding can potentially interfere with the activity and effectiveness of the Copper Peptide. Therefore, it is best to avoid using strong chelating agents like Citric Acid, Lactic Acid, or EDTA in the same formula as GHK-Cu, or applying products containing them immediately before or after your GHK-Cu serum.
- The current pH of 6.12 is likely acceptable. The main issue is the presence of chelating agents, not necessarily the pH itself within a reasonable range.
Will Copper Peptide (GHK-Cu) continue to be imported/sold?
- According to the staff, the company currently has no plans to discontinue importing Copper Peptide (GHK-Cu). It is a key ingredient used by many cosmetic manufacturers, so you should be able to purchase it for your future derma stamping plans.
It's great that you are seeing positive results and paying close attention to the science behind your formulations!
Related Products Mentioned
Pep®-Coll (Palmitoyl tripeptide-5)