Penetration Enhancers: DMI vs. Laurocapram Mix

You're asking if mixing Laurocapram (Water Soluble) and Laurocapram (Oil Soluble) can be a cost-effective alternative to Dimethyl Isosorbide (DMI) for enhancing the penetration of both water-soluble and oil-soluble ingredients.

Based on the product information:

• Dimethyl Isosorbide (DMI) is a versatile carrier known for enhancing the penetration of various ingredients, particularly highlighted for water-soluble actives. Its broad solubility profile (dissolves in water, glycols, alcohol, oils, silicones, etc.) allows it to function effectively in formulations containing both water and oil phases, helping to carry different types of ingredients.

• Laurocapram (Water Soluble) is specifically designed to enhance the penetration of water-soluble ingredients. The product description explicitly states it is not suitable for conveying oil-soluble ingredients.

• Laurocapram (Oil Soluble) is specifically designed to enhance the penetration of oil-soluble ingredients. The product description explicitly states it is not suitable for conveying water-soluble ingredients.

Crucially, the descriptions for both types of Laurocapram advise avoiding their use with other carriers (except 1,2-Hexanediol), as this may reduce the overall effectiveness.

Therefore, mixing Laurocapram (Water Soluble) and Laurocapram (Oil Soluble) is not recommended as a direct replacement for DMI to enhance the penetration of both water-soluble and oil-soluble substances simultaneously. Each Laurocapram type is specialized for one solubility phase, and combining them with each other or other carriers (besides 1,2-Hexanediol) is advised against.

If you need a carrier suitable for both water-soluble and oil-soluble ingredients, Phospholipid is mentioned in the product descriptions as an alternative option for this purpose.