Using Palmitamide MEA and Glycyrrhetinic Acid for Sensitive Skin

Based on research, both Palmitamide MEA and Glycyrrhetinic Acid (Enoxolone) are known for their ability to help soothe and reduce skin irritation, making them suitable for sensitive skin formulations.

• Palmitamide MEA: This ingredient is often used in products targeting allergic redness and irritation. It can be incorporated into cream, lotion, and potentially spray formulations, depending on the specific base and dissolution method. It typically requires heating in certain oils or glycols to dissolve before being added to the main formula.
• Glycyrrhetinic Acid (Enoxolone): Extracted from licorice, this ingredient offers anti-irritant and anti-inflammatory benefits. It can be used in various skincare products, including creams and lotions. Like Palmitamide MEA, it usually needs to be dissolved in glycols with heat before being added to the formulation.

Both Palmitamide MEA and Glycyrrhetinic Acid can generally be used together in the same formulation to enhance the soothing effect for sensitive skin. When formulating, it is important to follow the recommended mixing instructions for each ingredient, particularly regarding dissolution with heat in appropriate solvents (like glycols or certain oils), to ensure they are properly incorporated into your cream, lotion, or spray base.

Enhancing Moisturizing Properties

To significantly boost the moisturizing capabilities of your sensitive skin formulation, you can add ingredients known for their hydrating properties. Some excellent options include:

• Natural Moisturizing Amino Acids: This complex mimics the skin's natural moisturizing factors (NMF), helping to keep the skin soft and hydrated and supporting wound healing. It is water-soluble and can be added to various product types like creams, lotions, and serums.
• MOIST72™: A plant-derived sugar molecule that also mimics NMF, providing long-lasting and continuous hydration for up to 72 hours. It is particularly beneficial for dry and very dry skin and helps reduce irritation. It is water-soluble and should be added during the cooling phase of your formulation.
• Advanced Moisture Complex: This is a comprehensive blend of moisturizing ingredients designed to provide immediate and long-lasting hydration, improve skin barrier function, and prevent water loss. It is water-soluble and suitable for all skincare products.

By combining Palmitamide MEA and Glycyrrhetinic Acid for their soothing benefits with one or more of these powerful moisturizing ingredients, you can create a comprehensive formulation well-suited for sensitive and dry skin types.