Mixing Ingredients into Lotion

You asked about mixing Vitamin B3, NAG (Acetyl Glucosamine), Vitamin C, and Glycerin into Vaseline yellow lotion.

From the previous conversation, it was noted that Vitamin B3 (Niacinamide) and Vitamin C (L-Ascorbic Acid) are generally not compatible when mixed directly and should not be used together in the same formula.

You then chose to proceed with Vitamin C. The staff correctly pointed out that Vitamin C (L-Ascorbic Acid) is unstable in formulas containing water, which most lotions do. It oxidizes quickly and loses its effectiveness.

Therefore, if your Vaseline yellow lotion contains water (which is highly likely for a lotion), using Vitamin C (L-Ascorbic Acid) is not recommended for long-term stability and efficacy.

Recommended Approach

To effectively incorporate Vitamin C into a water-based lotion, it is best to use a stable derivative of Vitamin C. As suggested by the staff, Ethyl Ascorbic Acid or Perfect-C (Ascorbyl Tetraisopalmitate) are good alternatives.

• Ethyl Ascorbic Acid is a water-soluble, highly stable Vitamin C derivative that works well in water-based formulas like lotions. It is compatible with NAG (Acetyl Glucosamine) and Glycerin.
• Perfect-C (Ascorbyl Tetraisopalmitate) is an oil-soluble Vitamin C derivative that is also highly stable and effective. It can be incorporated into the oil phase of a lotion. It is compatible with NAG (Acetyl Glucosamine) and Glycerin.

NAG (Acetyl Glucosamine) and Glycerin are both water-soluble ingredients that can generally be mixed into a lotion base without significant compatibility issues. They work well with both Ethyl Ascorbic Acid and Perfect-C.

Summary

• You can mix NAG (Acetyl Glucosamine) and Glycerin into a lotion base.
• Avoid mixing Vitamin B3 (Niacinamide) and Vitamin C (L-Ascorbic Acid) together.
• Do not use Vitamin C (L-Ascorbic Acid) in a water-based lotion because it is unstable.
• For a stable Vitamin C in a lotion, use Ethyl Ascorbic Acid (water-soluble) or Perfect-C (Ascorbyl Tetraisopalmitate) (oil-soluble).
• NAG (Acetyl Glucosamine) and Glycerin are compatible with both Ethyl Ascorbic Acid and Perfect-C.