Why Climbazole is not recommended in rinse-off cleanser or face wash gel formulations

Climbazole is generally not recommended for use in rinse-off cleanser formulations, including face wash gels, primarily due to issues related to efficacy and formulation stability.

1. Low Efficacy due to Short Contact Time

Climbazole is an antifungal agent used to treat conditions like dandruff or seborrheic dermatitis. For any active ingredient to be effective, it requires sufficient contact time with the skin or scalp. Since cleansers (including face wash gels) are washed off quickly (typically within 30-60 seconds), the Climbazole does not have enough time to exert its therapeutic effect. This makes its inclusion largely ineffective and not cost-efficient.

2. Formulation Challenges (Solubility)

Climbazole has low solubility in water. Incorporating it into a stable, clear, high-water-content cleanser or gel requires the use of strong solubilizers or complex suspension systems. This can complicate the formulation process, potentially increase the cost, and sometimes lead to a finished product that is less stable or more irritating.

Conclusion for Face Wash Gel:
The same principles apply to a face wash gel. It is generally not recommended for use in any rinse-off product where the primary goal is therapeutic treatment, due to the short contact time. It is best suited for leave-on products (creams, lotions) or specialized shampoos designed for longer contact time.