Xanthan Gum, Penetration Enhancers, and Skin Absorption
คำถาม
What is the role of Xanthan Gum in a formulation, does it prevent active ingredients from penetrating the skin, and how does adding a penetration enhancer like Ethoxydiglycol affect skin absorption?
คำตอบ
Using Xanthan Gum and Skin Penetration Enhancers
Based on your question and the information provided, here's an explanation:
Xanthan Gum primarily functions as a thickening agent to create a gel texture in cosmetic formulations. Its main property is texture creation, and it does not directly possess properties that significantly enhance the penetration of active ingredients into the skin.
Using only Xanthan Gum mixed with active ingredients and water does not mean that the active ingredients cannot penetrate the skin at all. The skin still allows some degree of penetration for various substances, especially those with small molecular size and good compatibility with certain layers of the skin.
However, our skin layers consist of both water and oil components. When a formula's texture is compatible with both, it helps improve the efficiency of penetration into the skin.
Ethoxydiglycol is a substance that acts as a solvent and a skin penetration enhancer. Adding Ethoxydiglycol to a formula where Xanthan Gum is used as a gelling agent helps the active ingredients in the water base become more compatible with the skin's lipid layers, thus significantly improving the efficiency of delivering substances into the skin. Additionally, Ethoxydiglycol can also improve the solubility of certain ingredients in the formula.
Therefore, while using Xanthan Gum alone in a formula does not completely prevent active ingredients from entering the skin, adding a penetration enhancer like Ethoxydiglycol will help increase the efficiency of delivering those substances into the skin.
The necessity of adding a penetration enhancer is not limited to eye serum formulas. It depends on the type of active ingredient used, the desired concentration to be delivered, and the expected results from the formulation. If you want the active ingredients to perform optimally, considering the use of a penetration enhancer is important.
Relevant products:
- Xanthan Gum (available in various types such as clear gel type, smooth texture, normal texture, easy to spread)
- Ethoxydiglycol
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Ethoxydiglycol (e.q. Transcutol)