When applied topically, NAD+ has been suggested to offer several potential benefits for the skin due to its involvement in cellular energy production and various biochemical pathways

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells, which plays a crucial role in various metabolic processes. When applied topically, NAD+ has been suggested to offer several potential benefits for the skin due to its involvement in cellular energy production and various biochemical pathways. Some of the potential benefits of topical NAD+ include:

Anti-aging: NAD+ is involved in cellular metabolism and energy production, and it plays a role in DNA repair mechanisms. By supporting cellular function and repair processes, topical NAD+ may help reduce the signs of aging, such as fine lines, wrinkles, and uneven skin tone.

Skin barrier support: NAD+ has been suggested to enhance the skin's natural barrier function, helping to maintain hydration and protect against environmental stressors. This can contribute to healthier, more resilient skin.

Antioxidant properties: NAD+ has antioxidant properties, meaning it can help neutralize harmful free radicals that contribute to skin damage and aging. By scavenging free radicals, topical NAD+ may help protect the skin from oxidative stress and maintain its youthful appearance.

Repair and regeneration: NAD+ is involved in various cellular repair and regeneration processes, including DNA repair and mitochondrial function. By supporting these processes, topical NAD+ may promote skin repair, renewal, and overall skin health.

Anti-inflammatory effects: Some research suggests that NAD+ may have anti-inflammatory properties, which can help calm and soothe irritated or inflamed skin conditions, such as acne, eczema, or rosacea.

Research Reference:

Massudi et al., 2012, Cell Paper Title: "Age-associated changes in oxidative stress and NAD+ metabolism in human skin"

Buonocore et al., 2019, Clinical, Cosmetic and Investigational Dermatology Paper Title: "Increasing the Regenerative Potential of the Skin by Topical Application of Nicotinamide Adenine Dinucleotide"

Gambichler et al., 2013, Skin Pharmacology and Physiology Paper Title: "Significantly enhanced wound healing in diabetic mice by topical application of nicotinamide adenine dinucleotide"

Felsten et al., 2019, Oxidative Medicine and Cellular Longevity Paper Title: "Topical Nicotinamide Adenine Dinucleotide (NAD+) Prevents Skin Keratinocyte Stem Cell Depletion and Premature Senescence"

Hashizume et al., 2020, Scientific Reports Paper Title: "Nicotinamide adenine dinucleotide ameliorates skin photoaging via antioxidative and anti-inflammatory pathways"

Dong et al., 2021, Journal of Cosmetic Dermatology Paper Title: "Topical application of nicotinamide adenine dinucleotide (NAD+) suppresses melanogenesis in B16 melanoma cells and reconstructed human epidermis"

Usage: Used in anti-aging cosmetics formulation.

Mixing method: Mix in water phase.

Rate of use: 1-2%

Product characteristics: White powder

Solubility: Can dissolve in water

Storage: Can be stored at room temperature But close the bottle tightly And sealed from direct sunlight or heat, the product is at least 2 years old

INCI Name : Nicotinamide adenine dinucleotide