Fmoc-D-His(Trt)-OH
98%
- Product Code: 126684
Alias:
N-Fremoxycarbonyl-N'-trityl-D-histidine
CAS:
135610-90-1
| Molecular Weight: | 619.7 g./mol | Molecular Formula: | C₄₀H₃₃N₃O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where it serves as a protected form of histidine. The Fmoc group ensures selective deprotection during the synthesis process, while the Trt (trityl) group protects the imidazole side chain of histidine, preventing unwanted side reactions. This compound is essential for constructing peptides with histidine residues, which are crucial in many biologically active peptides and proteins. Its application is widespread in pharmaceutical research, drug development, and the study of protein-protein interactions.
Product Specification:
| Test | Specification |
|---|---|
| Purity (HPLC) | 98-100 |
| Specific Rotation [A]20/D(C=5, CHCL3) | 94-100 |
| Appearance | White To Light Yellow Powder |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $16.20 |
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| 5.000 | 10-20 days | $54.61 |
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| 25.000 | 10-20 days | $221.12 |
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Fmoc-D-His(Trt)-OH
Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where it serves as a protected form of histidine. The Fmoc group ensures selective deprotection during the synthesis process, while the Trt (trityl) group protects the imidazole side chain of histidine, preventing unwanted side reactions. This compound is essential for constructing peptides with histidine residues, which are crucial in many biologically active peptides and proteins. Its application is widespread in pharmaceutical research, drug development, and the study of protein-protein interactions.
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