Fmoc-D-Glu(OtBu)-OH
98%
- Product Code: 66181
Alias:
N-Fremoxycarbonyl-D-glutamic acid gamma-tert-butyl ester
CAS:
104091-08-9
| Molecular Weight: | 425.47 g./mol | Molecular Formula: | C₂₄H₂₇NO₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00077055 | |
| Melting Point: | 83-89 °C | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where it serves as a building block for constructing peptides. The Fmoc group protects the amino group during the synthesis process, while the tert-butyl ester group protects the carboxylic acid side chain of glutamic acid. This allows for selective deprotection and coupling steps, enabling the precise assembly of peptide chains. It is commonly employed in the production of therapeutic peptides, research peptides, and peptidomimetics, contributing to advancements in drug development and biochemical studies. Its stability and compatibility with various reagents make it a reliable choice for complex peptide synthesis workflows.
Product Specification:
| Test | Specification |
|---|---|
| Melting point | 90 94? |
| PURITYHPLC | 98 100% |
| SPECIFIC ROTATION A20DC1 IN DMF | 14 18 |
| APPEARANCE | WHITE TO LIGHT YELLOW POWDER |
| INFRARED SPECTROMETRY | Conforms to Structure |
| TLC ANALYSIS | ONE SPOT |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $12.58 |
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| 5.000 | 10-20 days | $36.18 |
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| 25.000 | 10-20 days | $165.96 |
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Fmoc-D-Glu(OtBu)-OH
Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where it serves as a building block for constructing peptides. The Fmoc group protects the amino group during the synthesis process, while the tert-butyl ester group protects the carboxylic acid side chain of glutamic acid. This allows for selective deprotection and coupling steps, enabling the precise assembly of peptide chains. It is commonly employed in the production of therapeutic peptides, research peptides, and peptidomimetics, contributing to advancements in drug development and biochemical studies. Its stability and compatibility with various reagents make it a reliable choice for complex peptide synthesis workflows.
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