Bleomycin sulfate
1.5-2.0 units/mg
- Product Code: 96454
Alias:
Bleomycin Sulfate; Bleomycin, Gloomycin
CAS:
9041-93-4
| Molecular Weight: | 1512.62 g./mol | Molecular Formula: | C₅₅H₈₅N₁₇O₂₅S₄ |
|---|---|---|---|
| EC Number: | 232-925-2 | MDL Number: | MFCD00070310 |
| Melting Point: | 200-204°C (dec.) | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
Bleomycin sulfate is primarily used in the treatment of various cancers, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and certain types of squamous cell carcinomas. It works by causing breaks in the DNA strands of cancer cells, which inhibits their ability to divide and proliferate. This chemotherapeutic agent is often administered intravenously or intramuscularly and is sometimes used in combination with other chemotherapy drugs to enhance its effectiveness. Additionally, bleomycin sulfate is utilized in pleurodesis, a procedure to prevent the recurrence of pleural effusions by inducing adhesion between the pleural layers. Its application in cancer therapy is carefully monitored due to potential side effects, particularly pulmonary toxicity, which can lead to lung fibrosis.
Product Specification:
| Test | Specification |
|---|---|
| BLEOMYCIN A2 | 55 % 70 % |
| BLEOMYCIN A2 B2 | 85 % 100 % |
| BLEOMYCIN B2 | 25 % 32 % |
| COPPER CU | 0 % 0.1 % |
| ENDOTOXIN ASSAY | 0 EU/mg 10 EU/mg |
| LOSS ON DRYING | 0-3 |
| APPEARANCE | White to Light Yellow Powder or Crystals |
| SOLUBILITY IN H2O | Colorless to Faint Yellow,Clear,20 mg/mL,H2O |
| PURITYUV-VIS | 90 % 100 % |
| NITROGEN | 15 % 17 % |
| E1at lambda max 290-291 nmanhydrous | 90 |
| CARBON ANHYDROUS | 42 % 45 % |
| Activity | 1.5 units/mg 2 units/mg |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | €165.15 |
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| 0.100 | 10-20 days | €656.38 |
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| 0.500 | 10-20 days | €2,321.35 |
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Bleomycin sulfate
Bleomycin sulfate is primarily used in the treatment of various cancers, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and certain types of squamous cell carcinomas. It works by causing breaks in the DNA strands of cancer cells, which inhibits their ability to divide and proliferate. This chemotherapeutic agent is often administered intravenously or intramuscularly and is sometimes used in combination with other chemotherapy drugs to enhance its effectiveness. Additionally, bleomycin sulfate is utilized in pleurodesis, a procedure to prevent the recurrence of pleural effusions by inducing adhesion between the pleural layers. Its application in cancer therapy is carefully monitored due to potential side effects, particularly pulmonary toxicity, which can lead to lung fibrosis.
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