G418 Sulfate (700U/mg)
98% biotech grade
- Product Code: 53564
CAS:
108321-42-2
| Molecular Weight: | 692.71 g./mol | Molecular Formula: | C₂₀H₄₀N₄O₁₀₂H₂SO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00058314 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8°C |
Product Description:
G418 Sulfate (700U/mg) is widely used in molecular biology and genetic research as a selective agent. It is commonly applied in cell culture experiments to select and maintain eukaryotic cells that have been genetically modified to express the neomycin resistance gene. When added to the culture medium, it inhibits protein synthesis in non-resistant cells, effectively killing them, while allowing the growth of resistant cells. This makes it a valuable tool for stable transfection studies, where researchers aim to integrate foreign DNA into the host genome. Additionally, it is used in the development of stable cell lines for producing recombinant proteins or studying gene function. Its effectiveness in selecting genetically engineered cells has made it a staple in biotechnology and pharmaceutical research.
Product Specification:
| Test | Specification |
|---|---|
| PETENCY | 700 ug/mg |
| WATER BY KARL FISCHER | 0 12% |
| SPECIFIC ROTATION A20DC0.3 H2O | 105.0 +121.0 |
| APPEARANCE | WHITE TO OFF-WHITE TO PALE CREAM POWDER |
| SOLUBILITY IN WATER | Colorless to Faint Yellow Clear to Very Slightly Hazy (50 mg/mL) |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.200 | 10-20 days | €32.98 |
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| 1.000 | 10-20 days | €130.85 |
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| 5.000 | 10-20 days | €506.01 |
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G418 Sulfate (700U/mg)
G418 Sulfate (700U/mg) is widely used in molecular biology and genetic research as a selective agent. It is commonly applied in cell culture experiments to select and maintain eukaryotic cells that have been genetically modified to express the neomycin resistance gene. When added to the culture medium, it inhibits protein synthesis in non-resistant cells, effectively killing them, while allowing the growth of resistant cells. This makes it a valuable tool for stable transfection studies, where researchers aim to integrate foreign DNA into the host genome. Additionally, it is used in the development of stable cell lines for producing recombinant proteins or studying gene function. Its effectiveness in selecting genetically engineered cells has made it a staple in biotechnology and pharmaceutical research.
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