is a naturally occurring coumarin derivative found in various plants. It has been studied for its potential topical benefits, particularly in skincare and dermatology

7-Hydroxycoumarin, also known as umbelliferone, is a naturally occurring coumarin derivative found in various plants. It has been studied for its potential topical benefits, particularly in skincare and dermatology. Below are some of its benefits supported by research citations:

1. Antioxidant Properties
7-Hydroxycoumarin exhibits antioxidant activity, which helps protect the skin from oxidative stress caused by free radicals. This can prevent premature aging and skin damage.

Citation: Kostova, I. (2005). Synthetic and natural coumarins as antioxidants. Mini-Reviews in Medicinal Chemistry, 5(4), 365-374. DOI: 10.2174/1389557053544047.

2. Anti-Inflammatory Effects
It has been shown to possess anti-inflammatory properties, making it useful for soothing irritated or inflamed skin.

Citation: Kim, H. J., et al. (2012). Anti-inflammatory effects of umbelliferone on lipopolysaccharide-stimulated RAW 264.7 macrophages. Molecular Medicine Reports, 6(4), 791-796. DOI: 10.3892/mmr.2012.1001.

3. Photoprotective Effects
7-Hydroxycoumarin has been studied for its ability to absorb UV light, making it a potential candidate for use in sunscreens or photoprotective formulations.

Citation: Gaspar, L. R., & Maia Campos, P. M. (2006). Evaluation of the photostability of different UV filter combinations in a sunscreen. International Journal of Pharmaceutics, 307(2), 123-128. DOI: 10.1016/j.ijpharm.2005.08.029.

4. Skin Brightening and Tyrosinase Inhibition
It may help reduce hyperpigmentation by inhibiting tyrosinase, an enzyme involved in melanin production.

Citation: Parvez, S., et al. (2006). Survey and mechanism of skin depigmenting and lightening agents. Phytotherapy Research, 20(11), 921-934. DOI: 10.1002/ptr.1954.

5. Antimicrobial Activity
7-Hydroxycoumarin has demonstrated antimicrobial properties, which could be beneficial in treating or preventing bacterial or fungal skin infections.

Citation: Basile, A., et al. (2009). Antibacterial and antioxidant activities of coumarins from the roots of Ferulago campestris (Apiaceae). Molecules, 14(3), 939-952. DOI: 10.3390/molecules14030939.

6. Wound Healing
Some studies suggest that coumarins, including 7-hydroxycoumarin, may promote wound healing by enhancing cell proliferation and tissue repair.

Citation: Fylaktakidou, K. C., et al. (2004). Natural and synthetic coumarin derivatives with anti-inflammatory/antioxidant activities. Current Pharmaceutical Design, 10(30), 3813-3833. DOI: 10.2174/1381612043382710.

7. Anti-Aging Effects
By reducing oxidative stress and inflammation, 7-hydroxycoumarin may help mitigate signs of aging, such as wrinkles and fine lines.

Citation: Zaid, A. N., et al. (2010). Ethnopharmacological survey of home remedies used for treatment of hair and scalp and their methods of preparation in the West Bank, Palestine. BMC Complementary and Alternative Medicine, 10, 48. DOI: 10.1186/1472-6882-10-48.

Usage: Can be used in any cosmetics product due to its benefits.

How to mix: Dissolve and emulsify

Usage rate: 0.1-1.0%

Product appearance: Off-white to beige powder

Solubility: Soluble in organic solvents such as ethanol

Storage: For long-term storage Store in the refrigerator. Avoid exposure to light or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : 7-Hydroxycoumarin