Eprotirome
≥99%
- Product Code: 100436
CAS:
355129-15-6
| Molecular Weight: | 487.14 g./mol | Molecular Formula: | C₁₈H₁₇Br₂NO₅ |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
Eprotirome is primarily used in the treatment of hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood. It functions as a thyroid hormone receptor agonist, specifically targeting the liver to enhance the metabolism of cholesterol and lipids. This action helps to lower LDL cholesterol (often referred to as "bad" cholesterol) and triglycerides while maintaining or even increasing HDL cholesterol ("good" cholesterol). Its liver-specific activity minimizes the risk of systemic side effects typically associated with thyroid hormone therapies, such as cardiovascular strain or muscle wasting. Eprotirome has shown promise in clinical trials for patients who do not respond adequately to statins or other lipid-lowering therapies. However, its development has faced challenges due to safety concerns, particularly regarding cartilage toxicity in long-term use. Despite these hurdles, it remains a potential therapeutic option for managing lipid disorders in carefully selected patient populations.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | €451.13 |
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Eprotirome
Eprotirome is primarily used in the treatment of hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood. It functions as a thyroid hormone receptor agonist, specifically targeting the liver to enhance the metabolism of cholesterol and lipids. This action helps to lower LDL cholesterol (often referred to as "bad" cholesterol) and triglycerides while maintaining or even increasing HDL cholesterol ("good" cholesterol). Its liver-specific activity minimizes the risk of systemic side effects typically associated with thyroid hormone therapies, such as cardiovascular strain or muscle wasting. Eprotirome has shown promise in clinical trials for patients who do not respond adequately to statins or other lipid-lowering therapies. However, its development has faced challenges due to safety concerns, particularly regarding cartilage toxicity in long-term use. Despite these hurdles, it remains a potential therapeutic option for managing lipid disorders in carefully selected patient populations.
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