Estradiol 3-sulfamate

≥99%

  • Product Code: 100471
  CAS:    172377-52-5
Molecular Weight: 351.46 g./mol Molecular Formula: C₁₈H₂₅NO₄S
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: Estradiol 3-sulfamate is primarily investigated for its potential use in hormone replacement therapy (HRT), particularly for managing symptoms of menopause such as hot flashes, vaginal dryness, and osteoporosis. Its sulfamate group enhances its bioavailability and prolongs its activity, making it a promising candidate for sustained estrogenic effects. Additionally, it has been studied for its potential neuroprotective properties, with research exploring its role in mitigating cognitive decline and neurodegenerative diseases like Alzheimer’s. The compound’s unique structure also allows it to act as a selective estrogen receptor modulator (SERM), offering targeted therapeutic benefits with reduced side effects compared to traditional estrogens. Its application in cancer therapy, particularly in hormone-sensitive cancers like breast cancer, is also under investigation due to its ability to modulate estrogen receptor activity.
Product Specification:
Test Specification
Appearance White To Off-white Solid
Purity (%) 98.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days Ft221,084.70
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-
0.005 10-20 days Ft442,169.39
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-
Estradiol 3-sulfamate
Estradiol 3-sulfamate is primarily investigated for its potential use in hormone replacement therapy (HRT), particularly for managing symptoms of menopause such as hot flashes, vaginal dryness, and osteoporosis. Its sulfamate group enhances its bioavailability and prolongs its activity, making it a promising candidate for sustained estrogenic effects. Additionally, it has been studied for its potential neuroprotective properties, with research exploring its role in mitigating cognitive decline and neurodegenerative diseases like Alzheimer’s. The compound’s unique structure also allows it to act as a selective estrogen receptor modulator (SERM), offering targeted therapeutic benefits with reduced side effects compared to traditional estrogens. Its application in cancer therapy, particularly in hormone-sensitive cancers like breast cancer, is also under investigation due to its ability to modulate estrogen receptor activity.
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