NVP-LGK974
99%
- Product Code: 101232
CAS:
1243244-14-5
| Molecular Weight: | 396.44 g./mol | Molecular Formula: | C₂₃H₂₀N₆O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD27501026 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
NVP-LGK974 is primarily used in research settings to study the Wnt signaling pathway, which plays a critical role in cell proliferation, differentiation, and tissue homeostasis. It is a potent inhibitor of Porcupine, an enzyme essential for the secretion of Wnt proteins. By blocking this enzyme, NVP-LGK974 helps researchers investigate the effects of Wnt signaling inhibition in various biological processes, including cancer development and stem cell regulation. Its application is particularly valuable in preclinical studies aimed at understanding the therapeutic potential of targeting Wnt signaling in diseases such as colorectal cancer, where aberrant Wnt activation is often observed. Additionally, it serves as a tool to explore the role of Wnt signaling in tissue regeneration and developmental biology.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White To Light Red To Light Brown To Tan Powder Or Crystals |
| Purity (%) | 98.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $740.53 |
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NVP-LGK974
NVP-LGK974 is primarily used in research settings to study the Wnt signaling pathway, which plays a critical role in cell proliferation, differentiation, and tissue homeostasis. It is a potent inhibitor of Porcupine, an enzyme essential for the secretion of Wnt proteins. By blocking this enzyme, NVP-LGK974 helps researchers investigate the effects of Wnt signaling inhibition in various biological processes, including cancer development and stem cell regulation. Its application is particularly valuable in preclinical studies aimed at understanding the therapeutic potential of targeting Wnt signaling in diseases such as colorectal cancer, where aberrant Wnt activation is often observed. Additionally, it serves as a tool to explore the role of Wnt signaling in tissue regeneration and developmental biology.
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