MT-DADMe-ImmA
≥98%
- Product Code: 101576
CAS:
653592-04-2
| Molecular Weight: | 293.39 g./mol | Molecular Formula: | C₁₃H₁₉N₅OS |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
MT-DADMe-ImmA is primarily utilized in the field of medicinal chemistry and biochemistry as a potent inhibitor of purine nucleoside phosphorylase (PNP). This enzyme plays a critical role in the purine salvage pathway, making it a target for therapeutic intervention in certain diseases.
One of the key applications of MT-DADMe-ImmA is in the treatment of T-cell malignancies and autoimmune disorders. By inhibiting PNP, it disrupts the metabolism of purine nucleosides, leading to the accumulation of toxic metabolites that selectively target and kill T-cells. This mechanism makes it a promising candidate for therapies aimed at controlling abnormal T-cell proliferation.
Additionally, MT-DADMe-ImmA has been studied for its potential in treating viral infections, particularly those caused by DNA viruses. The inhibition of PNP can reduce the availability of nucleosides necessary for viral replication, thereby limiting the spread of the virus.
Research is also ongoing to explore its use in combination therapies, where it may enhance the efficacy of other anticancer or antiviral drugs. Its specificity and potency make it a valuable tool in both clinical and experimental settings for understanding and manipulating purine metabolism.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | €209.90 |
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| 0.010 | 10-20 days | €314.84 |
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| 0.025 | 10-20 days | €535.19 |
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MT-DADMe-ImmA
MT-DADMe-ImmA is primarily utilized in the field of medicinal chemistry and biochemistry as a potent inhibitor of purine nucleoside phosphorylase (PNP). This enzyme plays a critical role in the purine salvage pathway, making it a target for therapeutic intervention in certain diseases.
One of the key applications of MT-DADMe-ImmA is in the treatment of T-cell malignancies and autoimmune disorders. By inhibiting PNP, it disrupts the metabolism of purine nucleosides, leading to the accumulation of toxic metabolites that selectively target and kill T-cells. This mechanism makes it a promising candidate for therapies aimed at controlling abnormal T-cell proliferation.
Additionally, MT-DADMe-ImmA has been studied for its potential in treating viral infections, particularly those caused by DNA viruses. The inhibition of PNP can reduce the availability of nucleosides necessary for viral replication, thereby limiting the spread of the virus.
Research is also ongoing to explore its use in combination therapies, where it may enhance the efficacy of other anticancer or antiviral drugs. Its specificity and potency make it a valuable tool in both clinical and experimental settings for understanding and manipulating purine metabolism.
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