NH125
97%
- Product Code: 101654
CAS:
278603-08-0
| Molecular Weight: | 524.5599999999999 g./mol | Molecular Formula: | C₂₇H₄₅IN₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07370143 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
NH125 is primarily used in research settings as a potent inhibitor of the enzyme N-myristoyltransferase (NMT). This enzyme plays a critical role in the post-translational modification of proteins, specifically by attaching myristic acid to the N-terminal glycine of various proteins. By inhibiting NMT, NH125 is employed to study the biological functions of myristoylated proteins, which are involved in numerous cellular processes, including signal transduction, membrane association, and protein-protein interactions. Researchers utilize NH125 to explore its potential therapeutic applications in diseases where NMT activity is dysregulated, such as certain cancers and infectious diseases. Additionally, it serves as a valuable tool in biochemical assays to better understand the mechanisms of protein myristoylation and its impact on cellular function.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Solid |
| Purity (%) | 96.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | Ft15,406.97 |
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| 0.005 | 10-20 days | Ft63,782.72 |
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| 0.025 | 10-20 days | Ft172,385.73 |
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NH125
NH125 is primarily used in research settings as a potent inhibitor of the enzyme N-myristoyltransferase (NMT). This enzyme plays a critical role in the post-translational modification of proteins, specifically by attaching myristic acid to the N-terminal glycine of various proteins. By inhibiting NMT, NH125 is employed to study the biological functions of myristoylated proteins, which are involved in numerous cellular processes, including signal transduction, membrane association, and protein-protein interactions. Researchers utilize NH125 to explore its potential therapeutic applications in diseases where NMT activity is dysregulated, such as certain cancers and infectious diseases. Additionally, it serves as a valuable tool in biochemical assays to better understand the mechanisms of protein myristoylation and its impact on cellular function.
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| Stable in pH range | - |
| Solubility | - |
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