PX-478 2HCl
97%
- Product Code: 102185
CAS:
685898-44-6
| Molecular Weight: | 394.12 g./mol | Molecular Formula: | C₁₃H₂₀Cl₄N₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
PX-478 2HCl is primarily used in research settings to study its effects on hypoxia-inducible factor-1α (HIF-1α). It is known to inhibit HIF-1α, a protein that plays a critical role in cellular responses to low oxygen levels. This inhibition makes it a valuable tool in cancer research, as HIF-1α is often overexpressed in tumors and contributes to their growth, survival, and resistance to treatment. By targeting HIF-1α, PX-478 2HCl helps researchers explore potential therapeutic strategies to disrupt tumor progression and enhance the effectiveness of other cancer treatments. Additionally, it is used in studies investigating conditions related to hypoxia, such as ischemic diseases, to better understand the underlying mechanisms and develop targeted therapies.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Yellow To Khaki To Red Powder |
| Purity (%) | 96.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $463.07 |
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PX-478 2HCl
PX-478 2HCl is primarily used in research settings to study its effects on hypoxia-inducible factor-1α (HIF-1α). It is known to inhibit HIF-1α, a protein that plays a critical role in cellular responses to low oxygen levels. This inhibition makes it a valuable tool in cancer research, as HIF-1α is often overexpressed in tumors and contributes to their growth, survival, and resistance to treatment. By targeting HIF-1α, PX-478 2HCl helps researchers explore potential therapeutic strategies to disrupt tumor progression and enhance the effectiveness of other cancer treatments. Additionally, it is used in studies investigating conditions related to hypoxia, such as ischemic diseases, to better understand the underlying mechanisms and develop targeted therapies.
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