Regorafenib Hydrochloride

≥99%

  • Product Code: 102270
  CAS:    835621-07-3
Molecular Weight: 519.28 g./mol Molecular Formula: C₂₁H₁₆Cl₂F₄N₄O₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: Regorafenib Hydrochloride is primarily used in the treatment of certain types of cancer. It is specifically indicated for patients with metastatic colorectal cancer who have previously been treated with other therapies. Additionally, it is used for advanced gastrointestinal stromal tumors (GIST) that cannot be surgically removed or have stopped responding to other treatments. The drug is also approved for hepatocellular carcinoma (HCC), a type of liver cancer, in patients who have previously been treated with sorafenib. The compound works by inhibiting multiple kinase enzymes involved in tumor growth, angiogenesis, and the tumor microenvironment. This helps to slow down or stop the progression of cancer by blocking the signals that promote cancer cell proliferation and blood vessel formation. Patients are typically administered this medication orally, and it is often used as part of a broader treatment plan that may include other therapies. Regular monitoring is essential to manage potential side effects, which can include fatigue, hand-foot skin reaction, hypertension, and gastrointestinal issues.
Product Specification:
Test Specification
Appearance Off White To White Solid
Purity (%) 98.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days $82.23
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0.010 10-20 days $132.89
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0.050 10-20 days $315.62
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0.250 10-20 days $689.38
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1.000 10-20 days $1,337.23
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Regorafenib Hydrochloride
Regorafenib Hydrochloride is primarily used in the treatment of certain types of cancer. It is specifically indicated for patients with metastatic colorectal cancer who have previously been treated with other therapies. Additionally, it is used for advanced gastrointestinal stromal tumors (GIST) that cannot be surgically removed or have stopped responding to other treatments. The drug is also approved for hepatocellular carcinoma (HCC), a type of liver cancer, in patients who have previously been treated with sorafenib. The compound works by inhibiting multiple kinase enzymes involved in tumor growth, angiogenesis, and the tumor microenvironment. This helps to slow down or stop the progression of cancer by blocking the signals that promote cancer cell proliferation and blood vessel formation. Patients are typically administered this medication orally, and it is often used as part of a broader treatment plan that may include other therapies. Regular monitoring is essential to manage potential side effects, which can include fatigue, hand-foot skin reaction, hypertension, and gastrointestinal issues.
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