BOC-D-HIS(3-BOM)-OH
98%
- Product Code: 104262
CAS:
99310-01-7
| Molecular Weight: | 375.42 g./mol | Molecular Formula: | C₁₉H₂₅N₃O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00076940 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
This chemical is widely used in peptide synthesis as a protecting group for histidine residues. Its primary application is to prevent unwanted side reactions during the formation of peptide bonds, ensuring the selective and efficient synthesis of complex peptides. The BOC (tert-butyloxycarbonyl) group protects the amino group, while the 3-BOM (benzyloxymethyl) group specifically shields the imidazole side chain of histidine. This dual protection is particularly useful in solid-phase peptide synthesis (SPPS), where it allows for the stepwise assembly of peptides with high precision. Additionally, it is employed in the production of peptide-based pharmaceuticals, where maintaining the integrity of histidine residues is crucial for biological activity. The compound is also utilized in research settings for the development of novel peptides and peptidomimetics, contributing to advancements in drug discovery and biochemical studies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | €29.44 |
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| 1.000 | 10-20 days | €73.13 |
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BOC-D-HIS(3-BOM)-OH
This chemical is widely used in peptide synthesis as a protecting group for histidine residues. Its primary application is to prevent unwanted side reactions during the formation of peptide bonds, ensuring the selective and efficient synthesis of complex peptides. The BOC (tert-butyloxycarbonyl) group protects the amino group, while the 3-BOM (benzyloxymethyl) group specifically shields the imidazole side chain of histidine. This dual protection is particularly useful in solid-phase peptide synthesis (SPPS), where it allows for the stepwise assembly of peptides with high precision. Additionally, it is employed in the production of peptide-based pharmaceuticals, where maintaining the integrity of histidine residues is crucial for biological activity. The compound is also utilized in research settings for the development of novel peptides and peptidomimetics, contributing to advancements in drug discovery and biochemical studies.
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