(S,R,S)-AHPC-Boc
≥95%
- Product Code: 105988
CAS:
1448189-98-7
| Molecular Weight: | 530.68 g./mol | Molecular Formula: | C₂₇H₃₈N₄O₅S |
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| Density: | Storage Condition: | -20°C, dry, sealed |
Product Description:
(S,R,S)-AHPC-Boc is primarily used in the field of medicinal chemistry and drug development as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). PROTACs are a novel class of bifunctional molecules designed to selectively degrade target proteins within cells, offering a promising approach for treating diseases caused by abnormal protein activity, such as cancer and neurodegenerative disorders.
This compound is particularly valuable due to its role in linking the target protein-binding ligand to the E3 ubiquitin ligase-recruiting moiety, which is essential for the ubiquitin-proteasome system to degrade the protein of interest. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during synthesis, allowing for precise control over the chemical reactions involved in constructing PROTAC molecules.
Researchers leverage (S,R,S)-AHPC-Boc to develop highly specific and potent degraders of disease-causing proteins, advancing the field of targeted protein degradation and enabling the exploration of new therapeutic strategies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿34,200.00 |
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(S,R,S)-AHPC-Boc
(S,R,S)-AHPC-Boc is primarily used in the field of medicinal chemistry and drug development as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). PROTACs are a novel class of bifunctional molecules designed to selectively degrade target proteins within cells, offering a promising approach for treating diseases caused by abnormal protein activity, such as cancer and neurodegenerative disorders.
This compound is particularly valuable due to its role in linking the target protein-binding ligand to the E3 ubiquitin ligase-recruiting moiety, which is essential for the ubiquitin-proteasome system to degrade the protein of interest. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during synthesis, allowing for precise control over the chemical reactions involved in constructing PROTAC molecules.
Researchers leverage (S,R,S)-AHPC-Boc to develop highly specific and potent degraders of disease-causing proteins, advancing the field of targeted protein degradation and enabling the exploration of new therapeutic strategies.
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