(S,R,S)-AHPC-PEG2-C4-Cl (VH032-PEG2-C4-Cl)
98%
- Product Code: 106733
CAS:
1835705-57-1
| Molecular Weight: | 651.26 g./mol | Molecular Formula: | C₃₂H₄₇ClN₄O₆S |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It serves as a key linker molecule that connects an E3 ligase ligand to a target protein binder, facilitating the degradation of specific proteins of interest. The inclusion of the PEG2 spacer enhances solubility and flexibility, optimizing the molecule's interaction with the target protein and the ubiquitin-proteasome system. Its application is significant in drug discovery and therapeutic research, especially in targeting disease-causing proteins that are traditionally difficult to inhibit with conventional small molecules.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $2,582.55 |
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(S,R,S)-AHPC-PEG2-C4-Cl (VH032-PEG2-C4-Cl)
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It serves as a key linker molecule that connects an E3 ligase ligand to a target protein binder, facilitating the degradation of specific proteins of interest. The inclusion of the PEG2 spacer enhances solubility and flexibility, optimizing the molecule's interaction with the target protein and the ubiquitin-proteasome system. Its application is significant in drug discovery and therapeutic research, especially in targeting disease-causing proteins that are traditionally difficult to inhibit with conventional small molecules.
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