Ac-WEHD-AFC

98%

  • Product Code: 107488
  CAS:    210344-99-3
Molecular Weight: 838.8 g./mol Molecular Formula: C₃₈H₃₇F₃N₈O₁₁
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, airtight, dry
Product Description: This compound is primarily used in biochemical research as a fluorogenic substrate for caspase-1 and other related caspases. It is instrumental in studying apoptosis and inflammation processes, as caspase-1 plays a critical role in these pathways. Researchers utilize it to measure caspase activity in vitro, enabling the assessment of enzyme kinetics and inhibitor screening. The AFC (7-amino-4-trifluoromethylcoumarin) moiety is cleaved upon caspase activation, releasing a fluorescent signal that can be quantified to determine enzymatic activity. This makes it a valuable tool in drug discovery and the study of cellular mechanisms underlying diseases like cancer and autoimmune disorders.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days €970.65
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Ac-WEHD-AFC
This compound is primarily used in biochemical research as a fluorogenic substrate for caspase-1 and other related caspases. It is instrumental in studying apoptosis and inflammation processes, as caspase-1 plays a critical role in these pathways. Researchers utilize it to measure caspase activity in vitro, enabling the assessment of enzyme kinetics and inhibitor screening. The AFC (7-amino-4-trifluoromethylcoumarin) moiety is cleaved upon caspase activation, releasing a fluorescent signal that can be quantified to determine enzymatic activity. This makes it a valuable tool in drug discovery and the study of cellular mechanisms underlying diseases like cancer and autoimmune disorders.
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