HM30181 mesylate (Encequidar mesylate)

98%

  • Product Code: 108520
  CAS:    849675-87-2
Molecular Weight: 784.830 g./mol Molecular Formula: C₃₉H₄₀N₆O₁₀S
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, airtight, dry
Product Description: HM30181 mesylate is primarily used as a P-glycoprotein (P-gp) inhibitor to enhance the oral bioavailability of certain drugs. It is often co-administered with chemotherapy agents that are substrates of P-gp, such as paclitaxel, to improve their absorption and effectiveness. By inhibiting P-gp, it prevents the efflux of these drugs from the gastrointestinal tract, allowing for higher concentrations to enter the bloodstream. This application is particularly valuable in cancer therapy, where it helps to maximize the therapeutic impact of orally administered anticancer drugs, potentially reducing the need for intravenous administration and improving patient convenience.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿7,497.00
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0.010 10-20 days ฿12,870.00
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HM30181 mesylate (Encequidar mesylate)
HM30181 mesylate is primarily used as a P-glycoprotein (P-gp) inhibitor to enhance the oral bioavailability of certain drugs. It is often co-administered with chemotherapy agents that are substrates of P-gp, such as paclitaxel, to improve their absorption and effectiveness. By inhibiting P-gp, it prevents the efflux of these drugs from the gastrointestinal tract, allowing for higher concentrations to enter the bloodstream. This application is particularly valuable in cancer therapy, where it helps to maximize the therapeutic impact of orally administered anticancer drugs, potentially reducing the need for intravenous administration and improving patient convenience.
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