Wortmannin
98%
- Product Code: 110658
CAS:
19545-26-7
| Molecular Weight: | 428.43 g./mol | Molecular Formula: | C₂₃H₂₄O₈ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00133927 | |
| Melting Point: | 234-240 °C | Boiling Point: | |
| Density: | Storage Condition: | -20℃ |
Product Description:
Wortmannin is widely used in biochemical research as a potent and specific inhibitor of phosphoinositide 3-kinases (PI3Ks). It is particularly valuable in studying the PI3K signaling pathway, which plays a critical role in cellular processes such as growth, proliferation, and survival. Researchers use it to investigate the effects of PI3K inhibition on cancer cells, as this pathway is often dysregulated in various cancers. Additionally, Wortmannin is employed in studies related to autophagy, as it can block the formation of autophagosomes, providing insights into cellular degradation mechanisms. Its ability to inhibit other kinases, such as mTOR and DNA-PK, also makes it a useful tool for exploring their roles in cellular functions.
Product Specification:
| Test | Specification |
|---|---|
| Carbon (C) | 63.5-65.4 |
| Melting Point | 234-240 |
| Purity (HPLC) | 98-100 |
| Appearance | White Or Off-White Powder |
| Infrared Spectrum | Conforms To Structure |
| Solubility | Pale Yellow Clear Solution (10MG/ML, Ethyl Acetate |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | $140.42 |
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| 0.005 | 10-20 days | $302.92 |
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Wortmannin
Wortmannin is widely used in biochemical research as a potent and specific inhibitor of phosphoinositide 3-kinases (PI3Ks). It is particularly valuable in studying the PI3K signaling pathway, which plays a critical role in cellular processes such as growth, proliferation, and survival. Researchers use it to investigate the effects of PI3K inhibition on cancer cells, as this pathway is often dysregulated in various cancers. Additionally, Wortmannin is employed in studies related to autophagy, as it can block the formation of autophagosomes, providing insights into cellular degradation mechanisms. Its ability to inhibit other kinases, such as mTOR and DNA-PK, also makes it a useful tool for exploring their roles in cellular functions.
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