GW5074
98%
- Product Code: 124742
CAS:
220904-83-6
| Molecular Weight: | 520.942 g./mol | Molecular Formula: | C₁₅H₈Br₂INO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 561.4℃ at 760 mmHg | |
| Density: | 2.248g/ml | Storage Condition: | -20℃ |
Product Description:
GW5074 is primarily utilized in research settings as a potent and selective inhibitor of c-Raf kinase, a key enzyme in the MAPK/ERK signaling pathway. This pathway is critical for cell proliferation, differentiation, and survival, making GW5074 a valuable tool for studying cellular processes and signaling mechanisms. Researchers often employ it to investigate the role of c-Raf in various diseases, including cancer, as its inhibition can help elucidate the molecular mechanisms driving tumor growth and progression. Additionally, GW5074 is used in studies exploring neurodegenerative diseases, as the MAPK/ERK pathway is implicated in neuronal survival and function. Its ability to selectively target c-Raf without significantly affecting other kinases makes it a precise tool for dissecting specific signaling pathways in experimental models.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Light To Yellow Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿1,100.00 |
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| 0.005 | 10-20 days | ฿2,990.00 |
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| 0.025 | 10-20 days | ฿9,990.00 |
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GW5074
GW5074 is primarily utilized in research settings as a potent and selective inhibitor of c-Raf kinase, a key enzyme in the MAPK/ERK signaling pathway. This pathway is critical for cell proliferation, differentiation, and survival, making GW5074 a valuable tool for studying cellular processes and signaling mechanisms. Researchers often employ it to investigate the role of c-Raf in various diseases, including cancer, as its inhibition can help elucidate the molecular mechanisms driving tumor growth and progression. Additionally, GW5074 is used in studies exploring neurodegenerative diseases, as the MAPK/ERK pathway is implicated in neuronal survival and function. Its ability to selectively target c-Raf without significantly affecting other kinases makes it a precise tool for dissecting specific signaling pathways in experimental models.
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